The E3 ligase ASB3 downregulates antiviral innate immunity by targeting MAVS for ubiquitin-proteasomal degradation.
E3 连接酶 ASB3 通过靶向 MAVS 进行泛素-蛋白酶体降解来下调抗病毒先天免疫
期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-024-01376-5
Cheng Mingyang, Lu Yiyuan, Wang Jiarui, Wang Haixu, Sun Yu, Zhao Wenhui, Wang Junhong, Shi Chunwei, Luo Jiawei, Gao Ming, Yu Tianxin, Wang Jianzhong, Guan Jiayao, Wang Nan, Yang Wentao, Jiang Yanlong, Huang Haibin, Yang Guilian, Cao Xin, Yang Dongqin, Wang Chunfeng, Zeng Yan
