日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural and functional mechanisms underlying activation gate dynamics and IFM motif accessibility in human Na(v)1.5

人类Na(v)1.5激活门动力学和IFM基序可及性的结构和功能机制

Biswas, Rupam; López-Serrano, Ana Laura; Purohit, Apoorva; Ramirez-Navarro, Angelina; Huang, Hsiang-Ling; Cheng, Xiaolin; Heissler, Sarah M; Deschênes, Isabelle; Chinthalapudi, Krishna

Discovery of Niclosamide Analogs with Potent Mitochondrial Uncoupling Activity and Reduced Mitochondrial Inhibition-Associated Toxicity

发现具有强效线粒体解偶联活性和降低线粒体抑制相关毒性的尼克酰胺类似物

Jiang, Haowen; Macorano, Alessio; Xing, Enming; Jedoui, Mohamed; Mohammed, Shabber; Lee, Vanessa; Cheng, Jeffrey; McDonough, Lain; Cheng, Xiaolin; Ye, Jiangbin; Li, Pui Kai

O-GlcNAc transferase plays dual antiviral roles by integrating innate immunity and lipid metabolism.

O-GlcNAc转移酶通过整合先天免疫和脂质代谢发挥双重抗病毒作用

Dong Hong, Liang Chenxi, Zhang Junjie, Wu Weidong, Kumar Nitesh, Liu Zihao, Sun Yajun, Liao Zhiwei, Cheng Xiaolin, Yu Yanbao, Zhang Yong, Holtzman Michael J, Li Jianrong, Gowdy Kymberly M, Thomas Paul G, Badjic Jovica D, Ma Anjun, Ma Qin, Yount Jacob S, Liu Shan-Lu, Wen Haitao

Prognostic, biological, and structural implications of FLT3-JMD point mutations in acute myeloid leukemia: an analysis of Alliance studies.

FLT3-JMD 点突变在急性髓系白血病中的预后、生物学和结构意义:联盟研究分析

Anabtawi Nadeen, Nicolet Deedra, Alotaibi Najla, Buelow Daelynn R, Orwick Shelley, Gregory Thomas, Raj Ruchika, Coleman Kennedy, Kolitz Jonathan E, Powell Bayard L, Blum William G, Baer Maria R, Byrd John C, Stock Wendy, Uy Geoffrey L, Mrózek Krzysztof, Eisfeld Ann-Kathrin, Cheng Xiaolin, Baker Sharyn D, Blachly James S

Structural basis of human Na(v)1.5 gating mechanisms

人类Na(v)1.5门控机制的结构基础

Biswas, Rupam; López-Serrano, Ana Laura; Purohit, Apoorva; Ramirez-Navarro, Angelina; Huang, Hsiang-Ling; Grandinetti, Giovanna; Cheng, Xiaolin; Heissler, Sarah M; Deschênes, Isabelle; Chinthalapudi, Krishna

TopMT-GAN: a 3D topology-driven generative model for efficient and diverse structure-based ligand design

TopMT-GAN:一种基于三维拓扑结构的高效多样化配体设计生成模型

Wang, Shen; Lin, Tong; Peng, Tianyi; Xing, Enming; Chen, Sijie; Kara, Levent Burak; Cheng, Xiaolin

Absolute and Relative Binding Free Energy Calculations of Nucleotides to Multiple Protein Classes

核苷酸与多种蛋白质类别的绝对和相对结合自由能计算

Purohit, Apoorva; Cheng, Xiaolin

Benchmarking Alchemical Relative Binding Free Energy Calculations for Nucleotide Binding to Multimeric ATPases

对用于核苷酸与多聚体ATP酶结合的炼金术相对结合自由能计算进行基准测试

Purohit, Apoorva; Cheng, Xiaolin

Role of vinculin in the structural dynamics of cadherin-catenin complexes and its implications for F-actin binding

黏着斑蛋白在钙黏蛋白-连环蛋白复合物结构动力学中的作用及其对F-肌动蛋白结合的影响

Hui, Benedict; Bu, Zimei; Cheng, Xiaolin

Rotation Conformational Effects of Selected Cytotoxic Cardiac Glycosides on Their Interactions with Na(+)/K(+)-ATPase

选定的细胞毒性强心苷的旋转构象效应对其与Na(+)/K(+)-ATP酶相互作用的影响

Ren, Yulin; Yang, Peirun; Gallucci, Judith C; Wang, Can; Cheng, Xiaolin; Wu, Sijin; Kinghorn, A Douglas