文献库，生知库 | 链接生命科学的每一步

Schäfer, Daniel; Prieto-Garcia, Cristian; Wang, Jianhui; Heinz, Marcel; Matkovic, Vigor; Kielkowski, Pavel; Hasselbeck, Sebastian; Shah, Varun Jayeshkumar; Knapp, Stefan; Hummer, Gerhard; Dikic, Ivan; Cheng, Xinlai

SP3

发表日期：2026

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A Chemically Induced CRISPR/dCas13(FCPF) Platform for Precise and Programmable RNA Regulation

一种化学诱导的CRISPR/dCas13(FCPF)平台，用于精确和可编程的RNA调控

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.5c01609

Hasselbeck, Sebastian; Wang, Jianhui; Bai, Zhaodai; Hüfner, Tobias; Hummer, Gerhard; Grote, Phillip; Cheng, Xinlai

信号转导

发表日期：2025

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Recent Advances in Covalent Drug Discovery

共价药物发现的最新进展

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph16050663

Schaefer, Daniel; Cheng, Xinlai

发表日期：2023

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Molecular Marvels: Small Molecules Paving the Way for Enhanced Gene Therapy

分子奇迹：小分子为增强基因治疗铺平道路

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph17010041

Hasselbeck, Sebastian; Cheng, Xinlai

基因治疗

发表日期：2023

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Pro-oxidant and lifespan extension effects of caffeine and related methylxanthines in Caenorhabditis elegans

咖啡因及相关甲基黄嘌呤类化合物对秀丽隐杆线虫的促氧化和延长寿命作用

期刊:Food Chemistry-X

影响因子:8.2

doi:10.1016/j.fochx.2019.100005

Li, Hanmei; Roxo, Mariana; Cheng, Xinlai; Zhang, Shaoxiong; Cheng, Haoran; Wink, Michael

C. elegans

发表日期：2019

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Essential role of mitochondrial Stat3 in p38(MAPK) mediated apoptosis under oxidative stress

线粒体Stat3在氧化应激下p38(MAPK)介导的细胞凋亡中发挥关键作用

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-017-15342-4

Cheng, Xinlai; Peuckert, Christiane; Wölfl, Stefan

Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.

新型靛玉红衍生物对 Janus 和 Src 家族激酶的双重抑制作用阻断了与人类胰腺癌细胞凋亡相关的组成型激活的 Stat3 信号传导

期刊:Molecular Oncology

影响因子:4.5

doi:10.1016/j.molonc.2012.10.013

Nam Sangkil, Wen Wei, Schroeder Anne, Herrmann Andreas, Yu Hua, Cheng Xinlai, Merz Karl-Heinz, Eisenbrand Gerhard, Li Hongzhi, Yuan Yate-Ching, Jove Richard

News, Notes, and Queries

新闻、简讯和问答

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-018-23431-1

Cheng, Xinlai; Peuckert, Christiane; Wölfl, Stefan; Kudlien, F

发表日期：1988

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Targeting the Spliceosomal Protein USP39 Through Allosteric Ligands and PROTAC-Induced Degradation

通过变构配体和PROTAC诱导降解靶向剪接体蛋白USP39

A Chemically Induced CRISPR/dCas13(FCPF) Platform for Precise and Programmable RNA Regulation

一种化学诱导的CRISPR/dCas13(FCPF)平台，用于精确和可编程的RNA调控

Recent Advances in Covalent Drug Discovery

共价药物发现的最新进展

Molecular Marvels: Small Molecules Paving the Way for Enhanced Gene Therapy

分子奇迹：小分子为增强基因治疗铺平道路

Pro-oxidant and lifespan extension effects of caffeine and related methylxanthines in Caenorhabditis elegans

咖啡因及相关甲基黄嘌呤类化合物对秀丽隐杆线虫的促氧化和延长寿命作用

Essential role of mitochondrial Stat3 in p38(MAPK) mediated apoptosis under oxidative stress

线粒体Stat3在氧化应激下p38(MAPK)介导的细胞凋亡中发挥关键作用

Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.

新型靛玉红衍生物对 Janus 和 Src 家族激酶的双重抑制作用阻断了与人类胰腺癌细胞凋亡相关的组成型激活的 Stat3 信号传导

News, Notes, and Queries

新闻、简讯和问答