日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Selective activation of pro-anti-IL-1β antibody enhances specificity for autoinflammatory disorder therapy.

选择性激活促抗IL-1β抗体可增强自身炎症性疾病治疗的特异性

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-021-94298-y
Lin Wen-Wei, Lu Yun-Chi, Huang Bo-Cheng, Chuang Chih-Hung, Cheng Yi-An, Chen I-Ju, Liu Hui-Ju, Ho Kai-Wen, Liao Tzu-Yi, Liu En-Shuo, Wu Ting-Yi, Chang Long-Sen, Hong Shih-Ting, Cheng Tian-Lu
免疫/内分泌
炎症
发表日期：2021
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Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer

人源化双特异性抗体（mPEG × HER2）可快速赋予聚乙二醇化纳米颗粒肿瘤特异性，用于乳腺癌的多模态成像

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-020-00680-9
Cheng, Yi-An; Wu, Tung-Ho; Wang, Yun-Ming; Cheng, Tian-Lu; Chen, I-Ju; Lu, Yun-Chi; Chuang, Kuo-Hsiang; Wang, Chih-Kuang; Chen, Chiao-Yun; Lin, Rui-An; Chen, Huei-Jen; Liao, Tzu-Yi; Liu, En-Shuo; Chen, Fang-Ming
肿瘤
HER2
肿瘤免疫
乳腺癌
Human
发表日期：2020
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Specific activation of pro-Infliximab enhances selectivity and safety of rheumatoid arthritis therapy

特异性激活前体英夫利昔单抗可增强类风湿性关节炎治疗的选择性和安全性

期刊:PLoS Biology
影响因子:7.2
doi:10.1371/journal.pbio.3000286
Lu, Yun-Chi; Chuang, Chih-Hung; Chuang, Kuo-Hsiang; Chen, I-Ju; Huang, Bo-Cheng; Lee, Wen-Han; Wang, Hsin-Ell; Li, Jia-Je; Cheng, Yi-An; Cheng, Kai-Wen; Wang, Jaw-Yuan; Hsieh, Yuan-Chin; Lin, Wen-Wei; Cheng, Tian-Lu
关节炎
发表日期：2019
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Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice

利用转座子介导的体细胞诱变筛选小鼠，鉴定与皮质畸形相关的基因。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-018-04880-8
I-Ling Lu ,Chien Chen ,Chien-Yi Tung ,Hsin-Hung Chen ,Jia-Ping Pan ,Chia-Hsiang Chang ,Jia-Shing Cheng ,Yi-An Chen ,Chun-Hung Wang ,Chia-Wei Huang ,Yi-Ning Kang ,Hsin-Yun Chang ,Lei-Li Li ,Kai-Ping Chang ,Yang-Hsin Shih ,Chi-Hung Lin ,Shang-Yeong Kwan ,Jin-Wu Tsai
细胞生物学
发表日期：2018
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Selective antibody activation through protease-activated pro-antibodies that mask binding sites with inhibitory domains

通过蛋白酶激活的前抗体选择性激活抗体，这些前抗体通过抑制性结构域掩盖结合位点。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-017-11886-7
Chen, I-Ju; Chuang, Chih-Hung; Hsieh, Yuan-Chin; Lu, Yun-Chi; Lin, Wen-Wei; Huang, Chien-Chiao; Cheng, Ta-Chun; Cheng, Yi-An; Cheng, Kai-Wen; Wang, Yeng-Tseng; Chen, Fang-Ming; Cheng, Tian-Lu; Tzou, Shey-Cherng
发表日期：2017
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