文献库，生知库 | 链接生命科学的每一步

Pneumocystis jirovecii Pneumonia: Retrospective Comparative Analysis of Clinical, Laboratory, and Radiographic Features in Human Immunodeficiency Virus and Nonhuman Immunodeficiency Virus Immunocompromised Patients

卡氏肺囊虫肺炎：人类免疫缺陷病毒和非人类免疫缺陷病毒免疫功能低下患者的临床、实验室和放射学特征的回顾性比较分析

期刊:Journal of Global Infectious Diseases

影响因子:1.1

doi:10.4103/jgid.jgid_99_25

Fang, Jianhua; Lai, Rongfan; Li, Jiayue; Huang, Jingyi; Lai, Hongyi; Cheng, Na; Xiang, Tianxin

Protective effects of mouse bone marrow mesenchymal stem cell-derived extracellular vesicles on radiation-induced epididymal cells damage via USP44/RBM14 axis

小鼠骨髓间充质干细胞来源的细胞外囊泡通过USP44/RBM14轴对辐射诱导的附睾细胞损伤发挥保护作用

期刊:Stem Cell Research & Therapy

影响因子:7.1

doi:10.1186/s13287-025-04782-9

Lingfeng Zhu # ，Jianping Zhang # ，Yaoyao Liang # ，Yuanhang Cheng # ，Na Lin ，Wenyi Deng ，Lingling Lin ，Jin Chen

ROS-ATM-CHK2 axis stabilizes HIF-1α and promotes tumor angiogenesis in hypoxic microenvironment

ROS-ATM-CHK2轴稳定HIF-1α，并在缺氧微环境中促进肿瘤血管生成

期刊:Oncogene

影响因子:6.9

doi:10.1038/s41388-025-03336-w

Ming Bai #,Pengzhi Xu #,Rong Cheng #,Na Li #,Sunrun Cao,Qiqiang Guo,Xiaoxun Wang,Chunlu Li,Ning Bai,Bo Jiang,Xuan Wu,Xiaoyu Song,Chen Sun,Mingfang Zhao,Liu Cao

Predictive factors for neoadjuvant combined immunotherapy in gastric adenocarcinoma: Focusing on the primitive enterocyte phenotype and PVR.

胃腺癌新辅助联合免疫疗法的预测因素：以原始肠细胞表型和 PVR 为重点

期刊:British Journal of Cancer

影响因子:6.8

doi:10.1038/s41416-025-03031-3

Wang Bingzhi, Wang Yinong, Zhu Yongjian, Guo Lei, Zeng Hua, Wu Shuai, Wang Long, Mu Jiali, Shao Xinxin, Cheng Na, Ying Jianming, Tian Yantao, Xue Liyan

Photothermal therapy combined with a STING agonist induces pyroptosis, and gasdermin D could be a new biomarker for guiding the treatment of pancreatic cancer

光热疗法联合STING激动剂可诱导细胞焦亡，而gasdermin D可能成为指导胰腺癌治疗的新型生物标志物。

期刊:Journal of Translational Medicine

影响因子:6.1

doi:10.1186/s12967-025-06247-2

Yanyan Hu # ，ErPeng Qi # ，Chao Yun # ，Xi Li # ，Fangyi Liu ，Zhigang Cheng ，Na Guan ，Qiong Wang ，Huixia Zhao ，Wenhua Xiao ，Liang Peng ，Jingwen Yang ，Xiaoling Yu

Effects of neutrophil granule proteins on sepsis-associated lymphopenia and their relationship with CD4+ T-cell pyroptosis

中性粒细胞颗粒蛋白对脓毒症相关淋巴细胞减少的影响及其与CD4+T细胞焦亡的关系

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2025.1507800

Jia-Yu Mao, Ya-Wen Xie, Xian-Li Lei, Jia-Hui Zhang, Wei Cheng, Na Cui

Prediction of human pathogenic start loss variants based on self-supervised contrastive learning

基于自监督对比学习的人类致病性起始丢失变异预测

期刊:BMC Biology

影响因子:4.5

doi:10.1186/s12915-025-02348-y

Liu, Jie; Fan, Henghui; Cheng, Na; Su, Yansen; Xia, Junfeng

发表日期：2025

文献求助收藏

DRP-PSM: Multi-Level Feature Integration Reveals Hierarchical Contributions to Pathogenic Synonymous Mutation Prediction

DRP-PSM：多层次特征整合揭示致病性同义突变预测的层级贡献

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.5c05407

Cai, Jinsong; Jin, Fangfang; Cheng, Na; Xia, Junfeng; Ye, Chen

发表日期：2025

文献求助收藏

Integrating causal human genetics and In vivo transcriptomics to uncover a shared lipid-centric architecture in metabolic and neurocognitive disease

整合因果人类遗传学和体内转录组学，揭示代谢和神经认知疾病中共同的以脂质为中心的结构

期刊:Frontiers in Molecular Biosciences

影响因子:4

doi:10.3389/fmolb.2025.1712198

Li, Yi; Ni, Zhu; Xia, Xiao-Yong; Cheng, Na; Bo, Yu; He, Junwen; He, Yang; Meng, Xiang-Yu; Wang, Xu; Xu, Xuan

The SynMall resource for characterizing the functional impact of synonymous variation

SynMall资源用于描述同义变异的功能影响

Pneumocystis jirovecii Pneumonia: Retrospective Comparative Analysis of Clinical, Laboratory, and Radiographic Features in Human Immunodeficiency Virus and Nonhuman Immunodeficiency Virus Immunocompromised Patients

卡氏肺囊虫肺炎：人类免疫缺陷病毒和非人类免疫缺陷病毒免疫功能低下患者的临床、实验室和放射学特征的回顾性比较分析

Protective effects of mouse bone marrow mesenchymal stem cell-derived extracellular vesicles on radiation-induced epididymal cells damage via USP44/RBM14 axis

小鼠骨髓间充质干细胞来源的细胞外囊泡通过USP44/RBM14轴对辐射诱导的附睾细胞损伤发挥保护作用

ROS-ATM-CHK2 axis stabilizes HIF-1α and promotes tumor angiogenesis in hypoxic microenvironment

ROS-ATM-CHK2轴稳定HIF-1α，并在缺氧微环境中促进肿瘤血管生成

Predictive factors for neoadjuvant combined immunotherapy in gastric adenocarcinoma: Focusing on the primitive enterocyte phenotype and PVR.

胃腺癌新辅助联合免疫疗法的预测因素：以原始肠细胞表型和 PVR 为重点

Photothermal therapy combined with a STING agonist induces pyroptosis, and gasdermin D could be a new biomarker for guiding the treatment of pancreatic cancer

光热疗法联合STING激动剂可诱导细胞焦亡，而gasdermin D可能成为指导胰腺癌治疗的新型生物标志物。

Effects of neutrophil granule proteins on sepsis-associated lymphopenia and their relationship with CD4+ T-cell pyroptosis

中性粒细胞颗粒蛋白对脓毒症相关淋巴细胞减少的影响及其与CD4+T细胞焦亡的关系

Prediction of human pathogenic start loss variants based on self-supervised contrastive learning

基于自监督对比学习的人类致病性起始丢失变异预测

DRP-PSM: Multi-Level Feature Integration Reveals Hierarchical Contributions to Pathogenic Synonymous Mutation Prediction

DRP-PSM：多层次特征整合揭示致病性同义突变预测的层级贡献

Integrating causal human genetics and In vivo transcriptomics to uncover a shared lipid-centric architecture in metabolic and neurocognitive disease

整合因果人类遗传学和体内转录组学，揭示代谢和神经认知疾病中共同的以脂质为中心的结构