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Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress

胰岛特异性锌转运蛋白-8（ZnT8）的下调可保护人类胰岛素瘤细胞免受炎症应激

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.RA119.010937

Chengfeng Merriman, Dax Fu

Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8

用于人类胰腺锌转运体 ZnT8 变构抑制和免疫检测的高度特异性单克隆抗体

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.RA118.005136

Chengfeng Merriman, Hua Li, Huilin Li, Dax Fu

A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells

针对活胰腺 β 细胞表面的一类血清抗 ZnT8 抗体

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.RA117.000195

Chengfeng Merriman, Qiong Huang, Wei Gu, Liping Yu, Dax Fu

Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells

胰岛素分泌与胰腺β细胞表面颗粒驻留锌转运体ZnT8显示的偶联

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.M116.772152

Qiong Huang, Chengfeng Merriman, Hao Zhang, Dax Fu

The PP-motif in luminal loop 2 of ZnT transporters plays a pivotal role in TNAP activation

ZnT 转运体腔内环 2 中的 PP 基序在 TNAP 激活中起关键作用

期刊:Biochemical Journal

影响因子:4.4

doi:10.1042/BCJ20160324

Shigeyuki Fujimoto, Tokuji Tsuji, Takashi Fujiwara, Taka-Aki Takeda, Chengfeng Merriman, Ayako Fukunaka, Yukina Nishito, Dax Fu, Eitan Hoch, Israel Sekler, Kazuhisa Fukue, Yusaku Miyamae, Seiji Masuda, Masaya Nagao, Taiho Kambe

发表日期：2016

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Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes

人类 ZnT8 蛋白的脂质调节锌转运活性与 2 型糖尿病风险相关

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.M116.764605

Chengfeng Merriman, Qiong Huang, Guy A Rutter, Dax Fu

Water molecules mediate zinc mobility in the bacterial zinc diffusion channel ZIPB

水分子介导细菌锌扩散通道 ZIPB 中的锌移动

Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress

胰岛特异性锌转运蛋白-8（ZnT8）的下调可保护人类胰岛素瘤细胞免受炎症应激

Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8

用于人类胰腺锌转运体 ZnT8 变构抑制和免疫检测的高度特异性单克隆抗体

A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells

针对活胰腺 β 细胞表面的一类血清抗 ZnT8 抗体

Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells

胰岛素分泌与胰腺β细胞表面颗粒驻留锌转运体ZnT8显示的偶联

The PP-motif in luminal loop 2 of ZnT transporters plays a pivotal role in TNAP activation

ZnT 转运体腔内环 2 中的 PP 基序在 TNAP 激活中起关键作用

Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes

人类 ZnT8 蛋白的脂质调节锌转运活性与 2 型糖尿病风险相关