B7-H3-mediated cis-inhibition of EGFR by a tumor-selective bispecific antibody enhances anti-tumor efficacy and minimizes toxicities.
通过肿瘤选择性双特异性抗体对 EGFR 进行 B7-H3 介导的顺式抑制，可增强抗肿瘤疗效并最大限度地减少毒性。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69703-7
Guan Jian, Chia Tiongsun, Li Bin, Zhu Tianyu, Liao Zhengguang, Deng Junjie, Fu Fenggen, Wu Weiwei, Liu Chengtao, Liu Ya, Li Ninghuan, Yue Lili, Cao Lei, Lu Jia, Zhu Mengjia, Ling Xiaomin, Zheng Huilin, Lin Shuming, Li Li, Zhou Shuaixiang, He Kaijie
