Chertkoff相关文献与解析，生知库 | 链接生命科学的每一步

Exploring delayed diagnosis in Gaucher disease: insights from a community survey and potential solutions

探讨戈谢病诊断延迟问题：来自社区调查的见解和潜在解决方案

Aragón, Diana Paulina Peña; Collin-Histed, Tanya; Abdelwahab, Magy; Espinosa, Jesús Villarrubia; Chertkoff, Raul; Balzekiene, Andre; Pacey, Jessica

发表日期：2026

文献求助收藏

A phase III, open-label clinical trial evaluating pegunigalsidase alfa administered every 4 weeks in adults with Fabry disease previously treated with other enzyme replacement therapies

一项 III 期开放标签临床试验，评估每 4 周一次的培尼加糖苷酶 alfa 对既往接受过其他酶替代疗法治疗的法布里病成人患者的疗效。

期刊:Journal of Inherited Metabolic Disease

影响因子:3.8

doi:10.1002/jimd.12795

Holida, Myrl; Linhart, Aleš; Pisani, Antonio; Longo, Nicola; Eyskens, François; Goker-Alpan, Ozlem; Wallace, Eric; Deegan, Patrick; Tøndel, Camilla; Feldt-Rasmussen, Ulla; Hughes, Derralynn; Sakov, Anat; Rocco, Rossana; Almon, Einat Brill; Alon, Sari; Chertkoff, Raul; Warnock, David G; Waldek, Stephen; Wilcox, William R; Bernat, John A

发表日期：2025

文献求助收藏

Head-to-head trial of pegunigalsidase alfa versus agalsidase beta in patients with Fabry disease and deteriorating renal function: results from the 2-year randomised phase III BALANCE study

在患有法布里病且肾功能恶化的患者中，培尼加糖酶α与阿加糖酶β的头对头试验：来自为期2年的随机III期BALANCE研究的结果

期刊:Journal of Medical Genetics

影响因子:3.7

doi:10.1136/jmg-2023-109445

Wallace, Eric L; Goker-Alpan, Ozlem; Wilcox, William R; Holida, Myrl; Bernat, John; Longo, Nicola; Linhart, Aleš; Hughes, Derralynn A; Hopkin, Robert J; Tøndel, Camilla; Langeveld, Mirjam; Giraldo, Pilar; Pisani, Antonio; Germain, Dominique Paul; Mehta, Ankit; Deegan, Patrick B; Molnar, Maria Judit; Ortiz, Damara; Jovanovic, Ana; Muriello, Michael; Barshop, Bruce A; Kimonis, Virginia; Vujkovac, Bojan; Nowak, Albina; Geberhiwot, Tarekegn; Kantola, Ilkka; Knoll, Jasmine; Waldek, Stephen; Nedd, Khan; Karaa, Amel; Brill-Almon, Einat; Alon, Sari; Chertkoff, Raul; Rocco, Rossana; Sakov, Anat; Warnock, David G

发表日期：2024

文献求助收藏

Safety and efficacy of pegunigalsidase alfa in patients with Fabry disease who were previously treated with agalsidase alfa: results from BRIDGE, a phase 3 open-label study

一项 BRIDGE 3 期开放标签研究的结果显示，在既往接受过阿加糖酶 alfa 治疗的法布里病患者中，培尼加糖酶 alfa 的安全性和有效性

期刊:Orphanet Journal of Rare Diseases

影响因子:3.5

doi:10.1186/s13023-023-02937-6

Linhart, Aleš; Dostálová, Gabriela; Nicholls, Kathy; West, Michael L; Tøndel, Camilla; Jovanovic, Ana; Giraldo, Pilar; Vujkovac, Bojan; Geberhiwot, Tarekegn; Brill-Almon, Einat; Alon, Sari; Chertkoff, Raul; Rocco, Rossana; Hughes, Derralynn

发表日期：2023

文献求助收藏

Novel Orally Administered Recombinant Anti-TNF Alpha Fusion Protein for the Treatment of Ulcerative Colitis: Results From a Phase 2a Clinical Trial

用于治疗溃疡性结肠炎的新型口服重组抗 TNF Alpha 融合蛋白：2a 期临床试验结果

期刊:Journal of Clinical Gastroenterology

影响因子:2.8

doi:10.1097/MCG.0000000000001314

Einat Almon, Yoseph Shaaltiel, Wisam Sbeit, Alex Fich, Doron Schwartz, Mattitiahu Waterman, Mali Szlaifer, Hadar Reuveni, Bat-Chen Amit-Cohen, Sari Alon, Raul Chertkoff, Alona Paz, Yaron Ilan

Molecular analysis of GALT gene in Argentinian population: Correlation with enzyme activity and characterization of a novel Duarte-like allele

阿根廷人群GALT基因的分子分析：与酶活性的相关性及一种新型杜阿尔特样等位基因的特征

期刊:Molecular Genetics and Metabolism Reports

影响因子:1.9

doi:10.1016/j.ymgmr.2020.100695

Crespo, Carolina; Eiroa, Hernán; Otegui, María Inés; Bonetto, Mara Cecilia; Chertkoff, Lilien; Gravina, Luis Pablo

GALT

发表日期：2020

文献求助收藏

Improvement in bone marrow infiltration in patients with type I Gaucher disease treated with taliglucerase alfa

使用taliglucerase alfa治疗I型戈谢病患者，可改善骨髓浸润。

期刊:Journal of Inherited Metabolic Disease

影响因子:3.8

doi:10.1007/s10545-018-0195-y

Zimran, Ari; Dinur, Tama; Revel-Vilk, Shoshana; Akkerman, Eric M; van Dussen, Laura; Hollak, Carla E M; Maayan, Hannah; Altarescu, Gheona; Chertkoff, Raul; Maas, Mario

发表日期：2018

文献求助收藏

Immunogenicity of glycans on biotherapeutic drugs produced in plant expression systems-The taliglucerase alfa story.

植物表达系统中生产的生物治疗药物上聚糖的免疫原性——taliglucerase alfa 的故事

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0186211

Rup Bonita, Alon Sari, Amit-Cohen Bat-Chen, Brill Almon Einat, Chertkoff Raul, Tekoah Yoram, Rudd Pauline M

免疫/内分泌

发表日期：2017

文献求助收藏

The family environment predicts long-term academic achievement and classroom behavior following traumatic brain injury in early childhood

家庭环境能够预测幼儿期创伤性脑损伤后的长期学业成就和课堂行为。

期刊:

影响因子:

doi:10.1037/neu0000351

Durber, Chelsea M; Yeates, Keith Owen; Taylor, H Gerry; Walz, Nicolay Chertkoff; Stancin, Terry; Wade, Shari L

神经科学

发表日期：2017

文献求助收藏

Impact of Proteinuria on Renal Outcomes in the BALANCE Trial

蛋白尿对 BALANCE 试验中肾脏结局的影响

Exploring delayed diagnosis in Gaucher disease: insights from a community survey and potential solutions

探讨戈谢病诊断延迟问题：来自社区调查的见解和潜在解决方案

A phase III, open-label clinical trial evaluating pegunigalsidase alfa administered every 4 weeks in adults with Fabry disease previously treated with other enzyme replacement therapies

一项 III 期开放标签临床试验，评估每 4 周一次的培尼加糖苷酶 alfa 对既往接受过其他酶替代疗法治疗的法布里病成人患者的疗效。

Head-to-head trial of pegunigalsidase alfa versus agalsidase beta in patients with Fabry disease and deteriorating renal function: results from the 2-year randomised phase III BALANCE study

在患有法布里病且肾功能恶化的患者中，培尼加糖酶α与阿加糖酶β的头对头试验：来自为期2年的随机III期BALANCE研究的结果

Safety and efficacy of pegunigalsidase alfa in patients with Fabry disease who were previously treated with agalsidase alfa: results from BRIDGE, a phase 3 open-label study

一项 BRIDGE 3 期开放标签研究的结果显示，在既往接受过阿加糖酶 alfa 治疗的法布里病患者中，培尼加糖酶 alfa 的安全性和有效性

Novel Orally Administered Recombinant Anti-TNF Alpha Fusion Protein for the Treatment of Ulcerative Colitis: Results From a Phase 2a Clinical Trial

用于治疗溃疡性结肠炎的新型口服重组抗 TNF Alpha 融合蛋白：2a 期临床试验结果

Molecular analysis of GALT gene in Argentinian population: Correlation with enzyme activity and characterization of a novel Duarte-like allele

阿根廷人群GALT基因的分子分析：与酶活性的相关性及一种新型杜阿尔特样等位基因的特征

Improvement in bone marrow infiltration in patients with type I Gaucher disease treated with taliglucerase alfa

使用taliglucerase alfa治疗I型戈谢病患者，可改善骨髓浸润。

Immunogenicity of glycans on biotherapeutic drugs produced in plant expression systems-The taliglucerase alfa story.

植物表达系统中生产的生物治疗药物上聚糖的免疫原性——taliglucerase alfa 的故事

The family environment predicts long-term academic achievement and classroom behavior following traumatic brain injury in early childhood

家庭环境能够预测幼儿期创伤性脑损伤后的长期学业成就和课堂行为。