日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Exposure to β-hydroxybutyrate reduces the operating set point and increases excitability in hippocampal circuitry of healthy mice

β-羟基丁酸酯暴露可降低健康小鼠海马回路的工作设定点并增加其兴奋性。

Zampieri, Thais Tessari; Higa, Guilherme Shigueto Vilar; Borges, Fernando S; Viana, Felipe José Costa; Cruvinel, Emily; Bentivoglio, Lucas Eduardo; Lugao, Ademar Benevolo; Ulrich, Henning; Britto, Luiz Roberto; Katti, Kattesh V; Chesne, Alton Michael; de Pasquale, Roberto

Green Nanotechnology and Phytochemical Mediated Production of Ketone Encapsulated Protein Nanoparticles-in vitro and in vivo Bioavailability Investigations.

绿色纳米技术和植物化学介导的酮包封蛋白纳米粒子的生产——体外和体内生物利用度研究。

Raphael Karikachery Alice, K Katti Kavita, Thipe Velaphi C, Hegde Prajna, Prakash Deepa, Hegde Anantkumar, Chesne Alton Michael, Katti Kattesh V

OECD workshop consensus report: Ethical considerations with respect to human derived products, specifically human serum, in OECD test guidelines

经合组织研讨会共识报告:经合组织检测指南中关于人源产品(特别是人血清)的伦理考量

Jacobs, Miriam N; Bult, Jan M; Cavanagh, Kevin; Chesne, Christophe; Delrue, Nathalie; Fu, Jianan; Grange, Emma; Langezaal, Ingrid; Misztela, Dominika; Murray, Jenny; Paparella, Martin; Stoddart, Gilly; Tonn, Torsten; Treasure, Carol; Tsukano, Masaaki; Versteegen, Rosemary

Toxicity Investigations of (R)-3-Hydroxybutyrate Glycerides In Vitro and in Male and Female Rats

(R)-3-羟基丁酸甘油酯体外及雄性和雌性大鼠毒性研究

Laurie C Dolan, Alice Raphael Karikachery, Velaphi C Thipe, Benjamin G Arceneaux, Kavita K Katti, Kattesh V Katti, Alton M Chesne

A phase 1b dose-escalation/expansion study of BET inhibitor RO6870810 in patients with advanced multiple myeloma

一项针对晚期多发性骨髓瘤患者的BET抑制剂RO6870810的1b期剂量递增/扩展研究

Ramasamy, Karthik; Nooka, Ajay; Quach, Hang; Htut, Myo; Popat, Rakesh; Liedtke, Michaela; Tuchman, Sascha A; Laubach, Jacob; Gasparetto, Cristina; Chanan-Khan, Asher; Hertzberg, Mark; deMario, Mark; Nueesch, Eveline; Chesne, Evelyne; Franjkovic, Izolda; Lechner, Katharina; Kornacker, Martin; Cho, Hearn Jay

Phase 1b study of the BET protein inhibitor RO6870810 with venetoclax and rituximab in patients with diffuse large B-cell lymphoma

在弥漫性大B细胞淋巴瘤患者中,BET蛋白抑制剂RO6870810联合维奈托克和利妥昔单抗的1b期研究

Dickinson, Michael; Briones, Javier; Herrera, Alex F; González-Barca, Eva; Ghosh, Nilanjan; Cordoba, Raul; Rutherford, Sarah C; Bournazou, Eirini; Labriola-Tompkins, Emily; Franjkovic, Izolda; Chesne, Evelyne; Brouwer-Visser, Jurriaan; Lechner, Katharina; Brennan, Barbara; Nüesch, Eveline; DeMario, Mark; Rüttinger, Dominik; Kornacker, Martin; Hutchings, Martin

Validation of in vitro methods for human cytochrome P450 enzyme induction: Outcome of a multi-laboratory study

人细胞色素P450酶诱导体外方法的验证:一项多实验室研究的结果

Bernasconi, Camilla; Pelkonen, Olavi; Andersson, Tommy B; Strickland, Judy; Wilk-Zasadna, Iwona; Asturiol, David; Cole, Thomas; Liska, Roman; Worth, Andrew; Müller-Vieira, Ursula; Richert, Lysiane; Chesne, Christophe; Coecke, Sandra

Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

利用人类多能干细胞生成肝星状细胞,可以进行肝纤维化的体外建模

Mar Coll, Luis Perea, Ruben Boon, Sofia B Leite, Julia Vallverdú, Inge Mannaerts, Ayla Smout, Adil El Taghdouini, Delia Blaya, Daniel Rodrigo-Torres, Isabel Graupera, Beatriz Aguilar-Bravo, Christophe Chesne, Mustapha Najimi, Etienne Sokal, Juan José Lozano, Leo A van Grunsven, Catherine M Verfailli

Limitations of galactose therapy in phosphoglucomutase 1 deficiency

磷酸葡萄糖变位酶1缺乏症中半乳糖疗法的局限性

Nolting, Kristine; Park, Julien H; Tegtmeyer, Laura C; Zühlsdorf, Andrea; Grüneberg, Marianne; Rust, Stephan; Reunert, Janine; Du Chesne, Ingrid; Debus, Volker; Schulze-Bahr, Eric; Baxter, Robert C; Wada, Yoshinao; Thiel, Christian; van Schaftingen, Emile; Fingerhut, Ralph; Marquardt, Thorsten

Rapid Diagnosis of 83 Patients with Niemann Pick Type C Disease and Related Cholesterol Transport Disorders by Cholestantriol Screening

通过胆甾醇筛查快速诊断83例尼曼匹克C型病及相关胆固醇转运障碍患者

Reunert, Janine; Fobker, Manfred; Kannenberg, Frank; Du Chesne, Ingrid; Plate, Maria; Wellhausen, Judith; Rust, Stephan; Marquardt, Thorsten