日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hippocampal cAMP regulates HCN channel function on two time scales with differential effects on animal behavior

海马 cAMP 在两个时间尺度上调节 HCN 通道功能,并对动物行为产生不同的影响。

Lyman, Kyle A; Han, Ye; Zhou, Chengwen; Renteria, Isabelle; Besing, Gai-Linn; Kurz, Jonathan E; Chetkovich, Dane M

The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels

TRIP8b 的结构和功能,它是超极化激活环核苷酸门控通道的辅助亚基

Han, Ye; Lyman, Kyle A; Foote, Kendall M; Chetkovich, Dane M

Current Opinions and Consensus for Studying Tremor in Animal Models

目前关于动物模型中震颤研究的观点和共识

Kuo, Sheng-Han; Louis, Elan D; Faust, Phyllis L; Handforth, Adrian; Chang, Su-Youne; Avlar, Billur; Lang, Eric J; Pan, Ming-Kai; Miterko, Lauren N; Brown, Amanda M; Sillitoe, Roy V; Anderson, Collin J; Pulst, Stefan M; Gallagher, Martin J; Lyman, Kyle A; Chetkovich, Dane M; Clark, Lorraine N; Tio, Murni; Tan, Eng-King; Elble, Rodger J

HCN channels in the hippocampus regulate active coping behavior

海马体中的HCN通道调节主动应对行为

Fisher, Daniel W; Han, Ye; Lyman, Kyle A; Heuermann, Robert J; Bean, Linda A; Ybarra, Natividad; Foote, Kendall M; Dong, Hongxin; Nicholson, Daniel A; Chetkovich, Dane M

Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease

储存耗竭诱导的h通道可塑性可挽救与阿尔茨海默病相关的通道病变

Musial, Timothy F; Molina-Campos, Elizabeth; Bean, Linda A; Ybarra, Natividad; Borenstein, Ronen; Russo, Matthew L; Buss, Eric W; Justus, Daniel; Neuman, Krystina M; Ayala, Gelique D; Mullen, Sheila A; Voskobiynyk, Yuliya; Tulisiak, Christopher T; Fels, Jasmine A; Corbett, Nicola J; Carballo, Gabriel; Kennedy, Colette D; Popovic, Jelena; Ramos-Franco, Josefina; Fill, Michael; Pergande, Melissa R; Borgia, Jeffrey A; Corbett, Grant T; Pahan, Kalipada; Han, Ye; Chetkovich, Dane M; Vassar, Robert J; Byrne, Richard W; Matthew Oh, M; Stoub, Travis R; Remy, Stefan; Disterhoft, John F; Nicholson, Daniel A

Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy

通过删除 TRIP8b 基因来减少丘脑和皮质 Ih 信号,可以构建人类失神性癫痫的小鼠模型。

Heuermann, Robert J; Jaramillo, Thomas C; Ying, Shui-Wang; Suter, Benjamin A; Lyman, Kyle A; Han, Ye; Lewis, Alan S; Hampton, Thomas G; Shepherd, Gordon M G; Goldstein, Peter A; Chetkovich, Dane M

Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b

鉴定HCN1和TRIP8b之间蛋白质-蛋白质相互作用的小分子抑制剂的方法

Han, Ye; Lyman, Kyle A; Clutter, Matt; Schiltz, Gary E; Ismail, Quratul-Ain; Cheng, Xiangying; Luan, Chi-Hao; Chetkovich, Dane M

Identification of Small-Molecule Inhibitors of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels

超极化激活环核苷酸门控通道小分子抑制剂的鉴定

Han, Ye; Lyman, Kyle; Clutter, Matt; Schiltz, Gary E; Ismail, Quratul-Ain; Prados, Diego Bleifuss; Luan, Chi-Hao; Chetkovich, Dane M

Differential expression of HCN subunits alters voltage-dependent gating of h-channels in CA1 pyramidal neurons from dorsal and ventral hippocampus

HCN亚基的差异表达改变了背侧和腹侧海马CA1锥体神经元中h通道的电压依赖性门控

Dougherty, Kelly A; Nicholson, Daniel A; Diaz, Laurea; Buss, Eric W; Neuman, Krystina M; Chetkovich, Dane M; Johnston, Daniel

Short- and long-term plasticity in CA1 neurons from mice lacking h-channel auxiliary subunit TRIP8b

缺乏h通道辅助亚基TRIP8b的小鼠CA1神经元的短期和长期可塑性

Brager, Darrin H; Lewis, Alan S; Chetkovich, Dane M; Johnston, Daniel