Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4(+)âT cells to confer protection against intestinal inflammation.
微生物代谢产物吲哚-3-丙酸驱动 CD4(+)T 细胞的线粒体呼吸，从而提供对肠道炎症的保护。
期刊:Nature Metabolism
影响因子:20.8
doi:10.1038/s42255-025-01396-6
Li Qing, de Oliveira Formiga Rodrigo, Puchois Virginie, Creusot Laura, Ahmad Ahmad Haidar, Amouyal Salomé, Campos-Ribeiro Márcio Augusto, Zhao Yining, Harris Danielle M M, Lasserre Frederic, Ellero-Simatos Sandrine, Guillou Hervé, Huang Zhan, Brot Loic, Hu Yuhang, Chollet Loic, Danne Camille, Scandola Cyril, Ledent Tatiana, Chevreux Guillaume, Argüello Rafael J, De Carvalho Bittencourt Marcelo, Bettinger Jessica, D'Aveni-Piney Maud, Moulin David, Schreiber Stefan, Aden Konrad, Rolhion Nathalie, Michel Marie-Laure, Wai Timothy, Sokol Harry
炎症
肠炎
T细胞
炎症/感染
代谢
微生物学
线粒体
细胞生物学
CD4
