日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation

Cas12a的桥螺旋是R环形成和RuvC激活的变构调节因子。

Ganguly, Chhandosee; Aribam, Swarmistha Devi; Dos Santos, Alberto Monteiro; Martin, Lindsie; Thomas, Leonard M; Shao, Yihan; Rajan, Rakhi

Structural integrity and side-chain interaction at the loop region of the bridge helix modulate Cas9 substrate discrimination

桥螺旋环区的结构完整性和侧链相互作用调节Cas9对底物的识别能力。

Wu, Difei; Snead, Sydney; Ganguly, Chhandosee; Babu, Kesavan; Li, Yue; Kathiresan, Venkatesan; Shen, Richard; Zhang, Xiaojun; Rajan, Rakhi; Qin, Peter Z

Biochemical and structural characterization of a reactive intermediate deaminase A homolog from Streptococcus sanguinis

对链球菌(Streptococcus sanguinis)中一种活性中间体脱氨酶A同源物的生化和结构表征

Benedict, Alexa B; Aquino, Adreana I; Buckner, Brandi A; Aribam, Swarmistha Devi; Ganguly, Chhandosee; Thomas, Leonard M; Bourne, Philip; Rajan, Rakhi; Downs, Diana M; Somalinga, Vijayakumar

391 Determining the effects of the pathogenic developmental and epileptic encephalopathy patient variant, SCN1B-p.R98C, on neuronal excitability

391 确定致病性发育和癫痫性脑病患者变异体 SCN1B-p.R98C 对神经元兴奋性的影响

Ganguly, Chhandosee; Martin, Lindsie; Aribam, Swarmistha; Thomas, Leonard M; Rajan, Rakhi; Vishwas, Sukriti; Singh, Sachin Kumar; Bashir, Bushra; Catalfio, Amanda; Kashima, Daniel T; Chen, Chunling; Isom, Lori L

Unity among the diverse RNA-guided CRISPR-Cas interference mechanisms

多种RNA引导的CRISPR-Cas干扰机制之间的统一性

Ganguly, Chhandosee; Rostami, Saadi; Long, Kole; Aribam, Swarmistha Devi; Rajan, Rakhi

Rational Engineering of CRISPR-Cas9 Nuclease to Attenuate Position-Dependent Off-Target Effects

通过合理设计 CRISPR-Cas9 核酸酶来减弱位置依赖性脱靶效应

Zuo, Zhicheng; Babu, Kesavan; Ganguly, Chhandosee; Zolekar, Ashwini; Newsom, Sydney; Rajan, Rakhi; Wang, Yu-Chieh; Liu, Jin

The Whole Is Bigger than the Sum of Its Parts: Drug Transport in the Context of Two Membranes with Active Efflux

整体大于部分之和:具有主动外排的双膜药物转运。

Rybenkov, Valentin V; Zgurskaya, Helen I; Ganguly, Chhandosee; Leus, Inga V; Zhang, Zhen; Moniruzzaman, Mohammad