Chi Lijun相关文献与解析，生知库 | 链接生命科学的每一步

Enhancer of zeste homolog 2 (Ezh2) is required in mouse Isl1-expressing progenitors for proper development of cardiac and skeletal hindlimb structures

增强子zeste同源物2 (Ezh2) 在小鼠表达Isl1的祖细胞中对于心脏和骨骼后肢结构的正常发育是必需的。

期刊:Biology Open

影响因子:1.7

doi:10.1242/bio.062550

Ammar, Hamna; Patolsky, Daniel B; Chi, Lijun; Caballero, Amalia N; Delgado-Olguín, Paul

Template-assisted sequence knockin rescues skeletal and cardiac muscle function in a deletion model of Duchenne muscular dystrophy.

模板辅助序列敲入可挽救杜氏肌营养不良症缺失模型中的骨骼肌和心肌功能。

期刊:Molecular Therapy

影响因子:12

doi:10.1016/j.ymthe.2025.05.005

Fatehi Sina, Rok Matthew J, Marks Ryan M, Huynh Emily, Kozman Natalie, Truong Hong Anh, Chi Lijun, Yan Bei, Khazeeva Enzhe, Delgado-Olguin Paul, Ivakine Evgueni A, Cohn Ronald D

心血管

发表日期：2025

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Analyses of NOTCH3 variants in Chinese patients with clinically diagnosed Alzheimer's disease and frontotemporal dementia

对中国临床诊断为阿尔茨海默病和额颞叶痴呆患者的 NOTCH3 变异进行分析

期刊:Alzheimers Research & Therapy

影响因子:7.6

doi:10.1186/s13195-025-01836-1

Nan, Haitian; Chu, Min; Yue, Ailing; He, Qianqian; Li, Jieying; Liu, Yanchen; Chi, Lijun; Liu, Xiaoyan; Peng, Guoping; Wu, Liyong

NTN-1 attenuates amyloid-Î²-mediated microglial neuroinflammation and memory impairment via the NF-ÎºB pathway and NLRP3 inflammasome in a rat model of Alzheimer's disease.

在阿尔茨海默病大鼠模型中，NTN-1 通过 NF-κB 通路和 NLRP3 炎症小体减弱淀粉样蛋白-β 介导的小胶质细胞神经炎症和记忆障碍

期刊:Frontiers in Aging Neuroscience

影响因子:4.5

doi:10.3389/fnagi.2025.1516399

Wang Tianhang, Liu Yanchen, Lu Yidan, Chi Lijun

VISTA Alleviates Microglia-Mediated Neuroinflammation After Cerebral Ischemia-Reperfusion Injury via Regulating ACOD1/Itaconic Acid Metabolism.

VISTA 通过调节 ACOD1/衣康酸代谢来减轻脑缺血再灌注损伤后小胶质细胞介导的神经炎症

期刊:Molecular Neurobiology

影响因子:4.3

doi:10.1007/s12035-025-05106-x

Sun Yilei, Liu Dan, Liu Yanchen, Chi Lijun

MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes

miR-30促进脂肪酸β-氧化和内皮细胞功能障碍，并且是糖尿病临床前模型中冠状动脉微血管功能障碍的循环生物标志物。

期刊:Cardiovascular Diabetology

影响因子:10.6

doi:10.1186/s12933-022-01458-z

Veitch, Shawn; Njock, Makon-Sébastien; Chandy, Mark; Siraj, M Ahsan; Chi, Lijun; Mak, HaoQi; Yu, Kai; Rathnakumar, Kumaragurubaran; Perez-Romero, Carmina Anjelica; Chen, Zhiqi; Alibhai, Faisal J; Gustafson, Dakota; Raju, Sneha; Wu, Ruilin; Zarrin Khat, Dorrin; Wang, Yaxu; Caballero, Amalia; Meagher, Patrick; Lau, Edward; Pepic, Lejla; Cheng, Henry S; Galant, Natalie J; Howe, Kathryn L; Li, Ren-Ke; Connelly, Kim A; Husain, Mansoor; Delgado-Olguin, Paul; Fish, Jason E

Formula feeding and immature gut microcirculation promote intestinal hypoxia, leading to necrotizing enterocolitis

配方奶喂养和肠道微循环发育不成熟会促进肠道缺氧，进而导致坏死性小肠结肠炎。

期刊:Disease Models & Mechanisms

影响因子:3.3

doi:10.1242/dmm.040998

Chen, Yong; Koike, Yuhki; Chi, Lijun; Ahmed, Abdalla; Miyake, Hiromu; Li, Bo; Lee, Carol; Delgado-Olguín, Paul; Pierro, Agostino

Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction

激活的 Hedgehog-GLI 信号通路导致先天性肾盂输尿管连接处梗阻

期刊:Journal of the American Society of Nephrology

影响因子:9.4

doi:10.1681/ASN.2017050482

Sheybani-Deloui, Sepideh; Chi, Lijun; Staite, Marian V; Cain, Jason E; Nieman, Brian J; Henkelman, R Mark; Wainwright, Brandon J; Potter, S Steven; Bagli, Darius J; Lorenzo, Armando J; Rosenblum, Norman D

Feasibility of up-regulating CD4(+)CD25(+) Tregs by IFN-γ in myasthenia gravis patients

IFN-γ上调重症肌无力患者CD4(+)CD25(+)调节性T细胞的可行性

期刊:BMC Neurology

影响因子:2.2

doi:10.1186/s12883-015-0419-9

Huang, Shuo; Wang, Weizhi; Chi, Lijun

SRSF1 as a promising biomarker and key player in the pathogenesis of Alzheimer's disease

SRSF1作为一种有前景的生物标志物和阿尔茨海默病发病机制中的关键因素

Enhancer of zeste homolog 2 (Ezh2) is required in mouse Isl1-expressing progenitors for proper development of cardiac and skeletal hindlimb structures

增强子zeste同源物2 (Ezh2) 在小鼠表达Isl1的祖细胞中对于心脏和骨骼后肢结构的正常发育是必需的。

Template-assisted sequence knockin rescues skeletal and cardiac muscle function in a deletion model of Duchenne muscular dystrophy.

模板辅助序列敲入可挽救杜氏肌营养不良症缺失模型中的骨骼肌和心肌功能。

Analyses of NOTCH3 variants in Chinese patients with clinically diagnosed Alzheimer's disease and frontotemporal dementia

对中国临床诊断为阿尔茨海默病和额颞叶痴呆患者的 NOTCH3 变异进行分析

NTN-1 attenuates amyloid-Î²-mediated microglial neuroinflammation and memory impairment via the NF-ÎºB pathway and NLRP3 inflammasome in a rat model of Alzheimer's disease.

在阿尔茨海默病大鼠模型中，NTN-1 通过 NF-κB 通路和 NLRP3 炎症小体减弱淀粉样蛋白-β 介导的小胶质细胞神经炎症和记忆障碍

VISTA Alleviates Microglia-Mediated Neuroinflammation After Cerebral Ischemia-Reperfusion Injury via Regulating ACOD1/Itaconic Acid Metabolism.

VISTA 通过调节 ACOD1/衣康酸代谢来减轻脑缺血再灌注损伤后小胶质细胞介导的神经炎症

MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes

miR-30促进脂肪酸β-氧化和内皮细胞功能障碍，并且是糖尿病临床前模型中冠状动脉微血管功能障碍的循环生物标志物。

Formula feeding and immature gut microcirculation promote intestinal hypoxia, leading to necrotizing enterocolitis

配方奶喂养和肠道微循环发育不成熟会促进肠道缺氧，进而导致坏死性小肠结肠炎。

Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction

激活的 Hedgehog-GLI 信号通路导致先天性肾盂输尿管连接处梗阻

Feasibility of up-regulating CD4(+)CD25(+) Tregs by IFN-γ in myasthenia gravis patients

IFN-γ上调重症肌无力患者CD4(+)CD25(+)调节性T细胞的可行性