日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Single-molecule imaging of small aggregates of IAPP in type 2 diabetes serum with rationally-designed antibody-like scaffolds

利用合理设计的抗体样支架对2型糖尿病血清中IAPP小聚集体进行单分子成像

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d5sc01427a
Lin, Jiacheng; Zhang, Yu P; Chia, Sean; Klenerman, David; Sormanni, Pietro; Vendruscolo, Michele
糖尿病
APP
代谢
发表日期：2026
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Using Generative Modeling to Endow with Potency Initially Inert Compounds with Good Bioavailability and Low Toxicity

利用生成模型赋予原本惰性的化合物以良好的生物利用度和低毒性

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.3c01777
Horne, Robert I; Wilson-Godber, Jared; González Díaz, Alicia; Brotzakis, Z Faidon; Seal, Srijit; Gregory, Rebecca C; Possenti, Andrea; Chia, Sean; Vendruscolo, Michele
毒理研究
发表日期：2024
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Maturation-dependent changes in the size, structure and seeding capacity of Aβ42 amyloid fibrils

Aβ42淀粉样蛋白原纤维的大小、结构和成核能力的成熟依赖性变化

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-024-05858-7
Miller, Alyssa; Chia, Sean; Klimont, Ewa; Knowles, Tuomas P J; Vendruscolo, Michele; Ruggeri, Francesco Simone
发表日期：2024
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Cellulose functionalized magnetic beads for high throughput glycosylation analysis in biotherapeutic modalities.

用于生物治疗模式中高通量糖基化分析的纤维素功能化磁珠

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-024-80649-y
Wan Corrine, Tay Shi Jie, Qiu Beiying, Chia Sean, Walsh Ian
发表日期：2024
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Adverse Local Tissue Reaction and Osteolysis After Ceramic-on-Ceramic Total Hip Arthroplasty

陶瓷对陶瓷全髋关节置换术后局部组织不良反应和骨溶解

期刊:Arthroplasty Today
影响因子:2.1
doi:10.1016/j.artd.2024.101584
Thever, Yogen; Goh, Lynne; Yau Li, Sam Fong; Siu Ling, Dahlia Ho; Rong Chia, Sean Yi; Ing How, Moo
发表日期：2024
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Multiplexed Digital Characterization of Misfolded Protein Oligomers via Solid-State Nanopores

利用固态纳米孔对错误折叠的蛋白质寡聚体进行多重数字表征

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.3c09335
Sandler, Sarah E; Horne, Robert I; Rocchetti, Sara; Novak, Robert; Hsu, Nai-Shu; Castellana Cruz, Marta; Faidon Brotzakis, Z; Gregory, Rebecca C; Chia, Sean; Bernardes, Gonçalo J L; Keyser, Ulrich F; Vendruscolo, Michele
发表日期：2023
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Enhanced surface nanoanalytics of transient biomolecular processes

瞬态生物分子过程的增强型表面纳米分析

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.abq3151
Miller, Alyssa; Chia, Sean; Toprakcioglu, Zenon; Hakala, Tuuli; Schmid, Roman; Feng, Yaduo; Kartanas, Tadas; Kamada, Ayaka; Vendruscolo, Michele; Ruggeri, Francesco Simone; Knowles, Tuomas P J
发表日期：2023
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Insight into muscle stem cell regeneration and mechanobiology

深入了解肌肉干细胞再生和力学生物学

期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-023-03363-y
Pang, Kuin Tian; Loo, Larry Sai Weng; Chia, Sean; Ong, Francesca Yi Teng; Yu, Hanry; Walsh, Ian
细胞生物学
发育与干细胞
干细胞
发表日期：2023
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Exploration and Exploitation Approaches Based on Generative Machine Learning to Identify Potent Small Molecule Inhibitors of α-Synuclein Secondary Nucleation

基于生成式机器学习的探索和利用方法，用于识别α-突触核蛋白二级成核的有效小分子抑制剂

期刊:Journal of Chemical Theory and Computation
影响因子:5.5
doi:10.1021/acs.jctc.2c01303
Horne, Robert I; Murtada, Mhd Hussein; Huo, Donghui; Brotzakis, Z Faidon; Gregory, Rebecca C; Possenti, Andrea; Chia, Sean; Vendruscolo, Michele
神经科学
发表日期：2023
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Structure-Based Discovery of Small-Molecule Inhibitors of the Autocatalytic Proliferation of α-Synuclein Aggregates

基于结构的α-突触核蛋白聚集体自催化增殖小分子抑制剂的发现

期刊:Molecular Pharmaceutics
影响因子:4.5
doi:10.1021/acs.molpharmaceut.2c00548
Chia, Sean; Faidon Brotzakis, Z; Horne, Robert I; Possenti, Andrea; Mannini, Benedetta; Cataldi, Rodrigo; Nowinska, Magdalena; Staats, Roxine; Linse, Sara; Knowles, Tuomas P J; Habchi, Johnny; Vendruscolo, Michele
神经科学
发表日期：2023
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