日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Blood measure of neuronal death is exponentially higher with age, especially in females, and halted in Alzheimer's disease by GM-CSF treatment

血液中神经元死亡的指标随年龄呈指数级增长,尤其是在女性中,而GM-CSF治疗可以阻止阿尔茨海默病患者的神经元死亡进程。

Sillau, Stefan H; Coughlan, Christina; Ahmed, Md Mahiuddin; Nair, Kavita; Araya, Paula; Galbraith, Matthew D; Ritchie, Alanna; Ching-Jung Wang, Athena; Elos, Mihret T; Bettcher, Brianne M; Espinosa, Joaquin M; Chial, Heidi J; Epperson, Neill; Boyd, Timothy D; Potter, Huntington

Higher Gene Expression Of Dynein Heavy Chains In The Dorsolateral Prefrontal Cortex Predict Lower Neuropathology Burden And Better Cognitive Outcomes In Individuals With Alzheimer’s Disease

背外侧前额叶皮层中动力蛋白重链基因表达水平较高预示着阿尔茨海默病患者神经病理负担较轻,认知功能预后较好。

Caramins, M; Halliday, G; McCusker, E; Trent, R J; Lucero, Esteban M; Brunetti, Tonya; Chial, Heidi J; Potter, Huntington; Gignoux, Chris

Human iPSC-derived retinal organoids develop robust Alzheimer's disease neuropathology

人诱导多能干细胞衍生的视网膜类器官会发展出强大的阿尔茨海默病神经病理学特征。

Ethan James # ,Anne Vielle # ,Karen Cusato # ,Helen Li ,Byoungin Lee ,Shama Parween ,Anna Howell ,Noah R Johnson ,Heidi J Chial ,Huntington Potter ,M Natalia Vergara

Red Light Therapy Attenuates Prolonged LED light Exposure‐Associated Neuropathology and Mediates Circadian Clock Genes ‐ Per1 and Bmal1 Expression in Rats' Basal Ganglia

红光疗法可减轻长时间LED光照射相关的神经病理学改变,并调节大鼠基底神经节中昼夜节律基因Per1和Bmal1的表达。

Sabbagh, Marwan N; Fleisher, Adam; Chen, Kewei; Rogers, Joseph; Berk, Camryn; Reiman, Eric; Pontecorvo, Michael; Mintun, Mark; Skovronsky, Daniel; Jacobson, Sandra A; Sue, Lucia I; Liebsack, Carolyn; Charney, Albert S; Cole, Lauren; Belden, Christine; Beach, Thomas G; Sillau, Stefan H; Ahmed, Md Mahiuddin; Coughlan, Christina M; Galbraith, Matthew D; Araya, Paula; Nair, Kavita V; Bettcher, Brianne M; Chial, Heidi J; Espinosa, Joaquin M; Potter, Huntington; Alexander, Madeline Wood; Honer, William G; Saloner, Rowan; Galea, Liisa AM; Bennett, David A A; Rabin, Jennifer S; Casaletto, Kaitlin B; Obajuluwa, Adejoke Olukayode; Babafemi, Laoye John; Ndianefo, Ogochukwu Jessica; Obajuluwa, Tiwalola Madoc; Lech, James Chrystopher; Okiki, Pius Abimbola; Obajuluwa, Adejoke Olukayode; Babafemi, Laoye John; Ndianefo, Ogochukwu Jessica; Obajuluwa, Tiwalola Madoc; Lech, James Chrystopher; Okiki, Pius Abimbola

Incongruences Between Facial Expression and Self-Reported Emotional Reactivity in Frontotemporal Dementia and Related Disorders

额颞叶痴呆及相关疾病患者的面部表情与自我报告的情绪反应之间的不一致

Pressman, Peter S; Chen, Kuan Hua; Casey, James; Sillau, Stefan; Chial, Heidi J; Filley, Christopher M; Miller, Bruce L; Levenson, Robert W

Building a Teleost Fish Traceability Program Based on Genetic Data from Pacific Panama Fish Markets

基于巴拿马太平洋鱼市的基因数据,构建硬骨鱼溯源系统

Díaz-Ferguson, Edgardo; Chial, Magaly; Gonzalez, Maribel; Muñoz, Edgardo; Chen, Olga; Durán, Ovidio; Vega, Angel Javier; Delgado, Carlos Ramos

Imipramine and olanzapine block apoE4-catalyzed polymerization of Aβ and show evidence of improving Alzheimer's disease cognition

丙咪嗪和奥氮平可阻断 apoE4 催化的 Aβ 聚合,并显示出改善阿尔茨海默病认知的证据

Noah R Johnson, Athena C-J Wang #, Christina Coughlan #, Stefan Sillau, Esteban Lucero, Lisa Viltz, Neil Markham, Cody Allen, A Ranjitha Dhanasekaran, Heidi J Chial, Huntington Potter

The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice

先天免疫系统刺激细胞因子 GM-CSF 可改善 Dp16 唐氏综合症小鼠的学习/记忆以及中间神经元和星形胶质细胞脑病理,并改善野生型小鼠的学习/记忆

Md Mahiuddin Ahmed, Athena Ching-Jung Wang, Mihret Elos, Heidi J Chial, Stefan Sillau, D Adriana Solano, Christina Coughlan, Leila Aghili, Paige Anton, Neil Markham, Vanesa Adame, Katheleen J Gardiner, Timothy D Boyd, Huntington Potter

Increased KIF11/ kinesin-5 expression offsets Alzheimer Aβ-mediated toxicity and cognitive dysfunction

KIF11/驱动蛋白-5表达增加可抵消阿尔茨海默病Aβ介导的毒性和认知功能障碍。

Esteban M Lucero ,Ronald K Freund ,Alexandra Smith ,Noah R Johnson ,Breanna Dooling ,Emily Sullivan ,Olga Prikhodko ,Md Mahiuddin Ahmed ,David A Bennett ,Timothy J Hohman ,Mark L Dell'Acqua ,Heidi J Chial ,Huntington Potter

Proteasome activity modulates amyloid toxicity

蛋白酶体活性调节淀粉样蛋白毒性

Galvin, John; Curran, Elizabeth; Arteaga, Francisco; Goossens, Alicia; Aubuchon-Endsley, Nicki; McMurray, Michael A; Moore, Jeffrey; Hansen, Kirk C; Chial, Heidi J; Potter, Huntington; Brodsky, Jeffrey L; Coughlan, Christina M