TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.
TGF-β 通过 II 型受体非依赖性信号传导诱导 TIAF1 自我聚集,从而导致阿尔茨海默病中淀粉样β斑块的产生
期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/cddis.2010.83
Lee M-H, Lin S-R, Chang J-Y, Schultz L, Heath J, Hsu L-J, Kuo Y-M, Hong Q, Chiang M-F, Gong C-X, Sze C-I, Chang N-S