日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ctDNA and tumor-based biomarkers of giredestrant response in acelERA breast cancer

ctDNA 和肿瘤相关生物标志物在 acelERA 乳腺癌治疗中对 giredestrant 反应的预测

Collier, Ann E; Hilz, Stephanie; Chibly, Alejandro M; Duan, Chunzhe; Pasquina, Lincoln W; Sun, Xiaopeng; Chavez-MacGregor, Mariana; Bardia, Aditya; Martín, Miguel; Lim, Elgene; Sohn, Joohyuk; Pérez-Moreno, Pablo Diego; Fernando, Tharu M; Moore, Heather M

Epiregulon: Single-cell transcription factor activity inference to predict drug response and drivers of cell states.

Epiregulon:通过单细胞转录因子活性推断来预测药物反应和细胞状态的驱动因素

Włodarczyk Tomasz, Lun Aaron, Wu Diana, Shi Minyi, Ye Xiaofen, Menon Shreya, Toneyan Shushan, Seidel Kerstin, Wang Liang, Tan Jenille, Chen Shang-Yang, Keyes Timothy, Chlebowski Aleksander, Waddell Adrian, Zhou Wei, Wang Yangmeng, Yuan Qiuyue, Guo Yu, Chen Liang-Fu, Daniel Bence, Hafner Antonina, He Meng, Chibly Alejandro, Liang Yuxin, Duren Zhana, Metcalfe Ciara, Hafner Marc, Siebel Christian W, Corces M Ryan, Yauch Robert, Xie Shiqi, Yao Xiaosai

CDK4/6i-treated HR+/HER2- breast cancer tumors show higher ESR1 mutation prevalence and more altered genomic landscape

接受 CDK4/6 抑制剂治疗的 HR+/HER2- 乳腺癌肿瘤表现出更高的 ESR1 突变率和更显著的基因组改变。

Chaudhary, Nayan; Chibly, Alejandro M; Collier, Ann; Martinalbo, Jorge; Perez-Moreno, Pablo; Moore, Heather M; Luhn, Patricia; Metcalfe, Ciara; Hafner, Marc

Neurotrophin signaling is a central mechanism of salivary dysfunction after irradiation that disrupts myoepithelial cells

神经营养因子信号传导是辐射后唾液功能障碍的核心机制,会破坏肌上皮细胞

Alejandro M Chibly, Vaishali N Patel, Marit H Aure, Mary C Pasquale; NIDCD/NIDCR Genomics and Computational Biology Core; Gemma E Martin, Mousa Ghannam, Julianne Andrade, Noah G Denegre, Colleen Simpson, David P Goldstein, Fei-Fei Liu, Isabelle M A Lombaert, Matthew P Hoffman

Evaluating the transcriptional landscape and cell-cell communication networks in chronically irradiated parotid glands

评估慢性照射腮腺中的转录景观和细胞间通讯网络

Brenna A Rheinheimer, Mary C Pasquale; NIDCD/NIDCR Genomics and Computational Biology Core; Kirsten H Limesand, Matthew P Hoffman, Alejandro M Chibly

Enteric viruses replicate in salivary glands and infect through saliva

肠道病毒在唾液腺中复制并通过唾液感染

S Ghosh, M Kumar, M Santiana, A Mishra, M Zhang, H Labayo, A M Chibly, H Nakamura, T Tanaka, W Henderson, E Lewis, O Voss, Y Su, Y Belkaid, J A Chiorini, M P Hoffman, N Altan-Bonnet

Salivary gland function, development, and regeneration

唾液腺的功能、发育和再生

Chibly, Alejandro M; Aure, Marit H; Patel, Vaishali N; Hoffman, Matthew P

Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function

Hs3st3a1 或 Hs3st3b1 酶的缺失会改变硫酸乙酰肝素,从而降低上皮形态发生和成人唾液腺功能

Vaishali N Patel, Dallas L Pineda, Elsa Berenstein, Belinda R Hauser, Sophie Choi, Michaela Prochazkova, Changyu Zheng, Corinne M Goldsmith, Toin H van Kuppevelt, Ashok Kulkarni, Yuefan Song, Robert J Linhardt, Alejandro M Chibly, Matthew P Hoffman

Generation of a Single-Cell RNAseq Atlas of Murine Salivary Gland Development

构建小鼠唾液腺发育的单细胞RNA测序图谱

Hauser, Belinda R; Aure, Marit H; Kelly, Michael C; Hoffman, Matthew P; Chibly, Alejandro M

aPKCζ-dependent Repression of Yap is Necessary for Functional Restoration of Irradiated Salivary Glands with IGF-1

aPKCζ 依赖的 Yap 抑制对于使用 IGF-1 恢复受辐射唾液腺的功能是必要的

Alejandro M Chibly, Wen Yu Wong, Maricela Pier, Hongqiang Cheng, Yongxin Mu, Ju Chen, Sourav Ghosh, Kirsten H Limesand