Cf-02, a novel benzamide-linked small molecule, blunts NF-κB activation and NLRP3 inflammasome assembly and improves acute onset of accelerated and severe lupus nephritis in mice
Cf-02 是一种新型苯甲酰胺连接的小分子，可抑制 NF-κB 活化和 NLRP3 炎症小体组装，并改善小鼠急性发作的加速型和重度狼疮性肾炎。
期刊:FASEB Journal
影响因子:4.2
doi:10.1096/fj.202100047R
Yang, Shin-Ruen; Hua, Kuo-Feng; Yang, Chih-Yu; Chen, Ann; Weng, Jui-Chun; Tsai, Yu-Ling; Wan, Chih-Jun; Wu, Chung-Yao; Lee, Chia-Chung; Chan, Jia-Feng; Hsieh, Chih-Yu; Hsu, Yu-Juei; Wu, Chia-Chao; Mukhopadhyay, Debabrata; Huang, Hsu-Shan; Liu, Feng-Cheng; Ka, Shuk-Man
肾炎
炎症
炎性小体
炎症/感染
NF-κB
LRP3
NLRP3
炎性小体
免疫/内分泌
