日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functional interrogation of contextually correct MYH7 variants using CRaTER-flox gene editing and contractility profiling

利用 CRaTER-flox 基因编辑和收缩性分析对上下文正确的 MYH7 变体进行功能性研究

Loiben, Alexander M; Chien, Wei-Ming; McKinstry, Ashley; Ahmed, Dania; Childers, Matthew C; Regnier, Michael; Murry, Charles E; Yang, Kai-Chun

Correction to "Potent, Selective Pyrrolopyrimidine PDE11A4 Inhibitors with Improved Pharmaceutical Properties"

对“具有改进药理特性的强效、选择性吡咯并嘧啶PDE11A4抑制剂”的更正

Mahmood, Shams Ul; Boddu, Rama Krishna; Eberhard, Jeremy; Hoffman, Charles S; Gordon, John; Colussi, Dennis; Childers, Wayne; Amurrio, Elvis; Danaher, Marie; Kelly, Michy P; Rotella, David P

Potent, Selective Pyrrolopyrimidine PDE11A4 Inhibitors with Improved Pharmaceutical Properties

具有改进药理特性的高效、选择性吡咯并嘧啶类PDE11A4抑制剂

Mahmood, Shams Ul; Boddu, Rama Krishna; Eberhard, Jeremy; Hoffman, Charles S; Gordon, John; Colussi, Dennis; Childers, Wayne; Amurrio, Elvis; Danaher, Marie; Kelly, Michy P; Rotella, David P

Combinatorial chemistry identifies additional compounds that selectively inhibit DLK-dependent retrograde signaling while minimally affecting other axonal roles of DLK

组合化学鉴定出一些化合物,这些化合物能够选择性地抑制DLK依赖的逆行信号传导,同时对DLK的其他轴突功能影响甚微。

Zhang, Xiaotian; Jeong, Heykyeong; Melenski, Edward; Gordon, John; Childers, Wayne E; Thomas, Gareth M

Independent centromeric expansions define giant hornet genomes

独立的着丝粒扩增定义了巨型大黄蜂的基因组

Ontano, Andrew; Sim, Sheina B; Jenkins, Jerry; Geib, Scott M; Childers, Anna K; Scheffler, Brian; Vaughn, Justin

MC-100093, a synthetic beta-lactam compound, and ceftriaxone modulate nicotine consumption, neuroinflammation and glutamatergic transporters in a nicotine self-administration mouse model

MC-100093(一种合成β-内酰胺类化合物)和头孢曲松在尼古丁自我给药小鼠模型中调节尼古丁消耗、神经炎症和谷氨酸能转运蛋白。

Alotaibi, Jawaher A; Alasmari, Fawaz; Albaker, Awatif B; Alrashedi, Fatin A; Mohany, Mohamed; Alshammari, Musaad A; AlAsmari, Abdullah F; Al-Rejaie, Salim S; Childers, Wayne E; Abou-Gharbia, Magid; Sari, Youssef

In silico conformational dynamics of the α-actinin-2 actin-binding domain upon phosphorylation

α-辅肌动蛋白-2肌动蛋白结合域磷酸化后的计算机模拟构象动力学

Tigro, Helene; Childers, Matthew C; Regnier, Michael; Solís, Christopher

Nitrite supplementation alleviates cerebrovascular dysfunction in chronically stressed mice, but cognitive decline remains

亚硝酸盐补充剂可缓解慢性应激小鼠的脑血管功能障碍,但认知能力下降仍然存在。

Burrage, Emily; Coblentz, Tyler; Prabhu, Saina S; Eminhizer, Nicole M; Childers, Ryan; Bryner, Randall W; Lewis, Sara E; Maxwell, Brooke A; DeVallance, Evan R; Kelley, Eric E; Chantler, Paul D

Toward personalizing prosthesis prescription: A take-home study of three microprocessor-controlled prosthetic knees: A randomized crossover study

迈向假肢处方个性化:三款微处理器控制假肢膝关节的居家使用研究:一项随机交叉研究

Herrin, Kinsey; Kestur, Sujay; Zhou, Sixu; O'Sullivan, Gwyn; Snow, Teresa; Childers, Walter Lee; Young, Aaron

MC-350013 and Corylin Emerge as Promising Neuroprotective Agents through Dual Targeting of xCT and GLT-1

MC-350013 和 Corylin 通过双重靶向 xCT 和 GLT-1 成为有前景的神经保护剂

Alsikhan, Rawan S; Alshehri, Mohammed M; Alqahtani, Qamraa H; Alanazi, Mohammed Mufadhe; Mohammed, Adil Shareef; AlAsmari, Abdullah F; Sari, Youssef; Childers, Wayne E; Abou-Gharbia, Magid; Alkhelb, Dalal; Alasmari, Fawaz