日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Biophysical characterization of blood coagulation factor VIII binding to lipid nanodiscs that mimic activated platelet surfaces

对模拟活化血小板表面的脂质纳米盘与血液凝固因子VIII结合的生物物理学表征

期刊:Journal of Thrombosis and Haemostasis
影响因子:5
doi:10.1016/j.jtha.2024.11.003
Avery, Nathan G; Young, Isabelle R; Lu, Selena; Vaughan, Jordan D; Korus, Patrick S; Richardson, Tera N; Childers, Kenneth C; Smirnov, Serge L; Spiegel, P Clint Jr
血小板
发表日期：2025
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Atomistic Mechanism of Lipid Membrane Binding for Blood Coagulation Factor VIII with Molecular Dynamics Simulations on a Microsecond Time Scale

利用微秒时间尺度分子动力学模拟揭示血液凝固因子VIII与脂质膜结合的原子级机制

期刊:Journal of Physical Chemistry B
影响因子:2.9
doi:10.1021/acs.jpcb.4c06575
Avery, Nathan G; Childers, Kenneth C; McCarty, James; Spiegel, Paul Clinton
发表日期：2025
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Humanization and functional characterization of enhanced coagulation factor IX variants identified through ancestral sequence reconstruction

通过祖先序列重建鉴定的增强型凝血因子IX变体的人源化和功能表征

期刊:Journal of Thrombosis and Haemostasis
影响因子:5
doi:10.1016/j.jtha.2023.11.010
Coyle, Christopher W; Knight, Kristopher A; Brown, Harrison C; George, Stephan N; Denning, Gabriela; Branella, Gianna M; Childers, Kenneth C; Spiegel, P Clint; Spencer, H Trent; Doering, Christopher B
Human
发表日期：2024
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Structural basis for inhibition of coagulation factor VIII reveals a shared antigenic hotspot on the C1 domain

凝血因子VIII抑制的结构基础揭示了C1结构域上的一个共同抗原热点。

期刊:Journal of Thrombosis and Haemostasis
影响因子:5
doi:10.1016/j.jtha.2024.05.024
Childers, Kenneth C; Cowper, Ben; Vaughan, Jordan D; McGill, Juliet R; Davulcu, Omar; Lollar, Pete; Doering, Christopher B; Coxon, Carmen H; Spiegel, Paul C Jr
发表日期：2024
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Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor

凝血因子VIII与患者来源的抗C1结构域抗体抑制剂结合的结构

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2023020181
Childers, Kenneth C; Avery, Nathan G; Estrada Alamo, Kevin A; Davulcu, Omar; Haynes, Rose Marie; Lollar, Pete; Doering, Christopher B; Coxon, Carmen H; Spiegel, P Clint
发表日期：2023
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Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII.

与含磷脂酰丝氨酸的膜稳定结合需要血液凝固因子 VIII 串联 C 结构域中保守的精氨酸残基

期刊:Frontiers in Molecular Biosciences
影响因子:4
doi:10.3389/fmolb.2022.1040106
Peters Shaun C, Childers Kenneth C, Mitchell Corbin E, Avery Nathan G, Reese Steven S Jr, Mitchell Cristopher, Wo Serena W, Swanson Christopher D, Brison Caileen M, Spiegel P Clint Jr
发表日期：2022
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Structure of blood coagulation factor VIII in complex with an anti-C1 domain pathogenic antibody inhibitor

血液凝固因子VIII与抗C1结构域致病性抗体抑制剂复合物的结构

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2020008940
Gish, Joseph S; Jarvis, Lexi; Childers, Kenneth C; Peters, Shaun C; Garrels, Connor S; Smith, Ian W; Spencer, H Trent; Doering, Christopher B; Lollar, Pete; Spiegel, P Clint
发表日期：2021
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Structure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor

血液凝固因子VIII与抗C2结构域非经典致病性抗体抑制剂复合物的结构

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2021.697602
Ronayne, Estelle K; Peters, Shaun C; Gish, Joseph S; Wilson, Celena; Spencer, H Trent; Doering, Christopher B; Lollar, Pete; Spiegel, P Clint Jr; Childers, Kenneth C
发表日期：2021
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Synergistic mutations in soluble guanylyl cyclase (sGC) reveal a key role for interfacial regions in the sGC activation mechanism.

可溶性鸟苷酸环化酶 (sGC) 的协同突变揭示了界面区域在 sGC 激活机制中的关键作用

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.RA119.011010
Childers Kenneth C, Yao Xin-Qiu, Giannakoulias Sam, Amason Joshua, Hamelberg Donald, Garcin Elsa D
其它
发表日期：2019
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Structure/function of the soluble guanylyl cyclase catalytic domain

可溶性鸟苷酸环化酶催化结构域的结构/功能

期刊:Nitric Oxide-Biology and Chemistry
影响因子:3.2
doi:10.1016/j.niox.2018.04.008
Childers, Kenneth C; Garcin, Elsa D
发表日期：2018
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