Ching Wooen相关文献与解析，生知库 | 链接生命科学的每一步

Borrelia burgdorferi serine protease HtrA is a pleiotropic regulator of stress response, motility, flagellar hemostasis, and infectivity

伯氏疏螺旋体丝氨酸蛋白酶HtrA是应激反应、运动性、鞭毛止血和感染性的多效性调节因子。

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-07781-x

Zhang, Kai; Sze, Ching Wooen; Zhao, Hang; Liu, Jun; Li, Chunhao

炎症/感染

发表日期：2025

文献求助收藏

Lactate dehydrogenase is the Achilles' heel of Lyme disease bacterium Borreliella burgdorferi.

乳酸脱氢酶是莱姆病细菌伯氏疏螺旋体的阿喀琉斯之踵

期刊:mBio

影响因子:4.7

doi:10.1128/mbio.03728-24

Sze Ching Wooen, Lynch Michael J, Zhang Kai, Neau David B, Ealick Steven E, Crane Brian R, Li Chunhao

微生物学

发表日期：2025

文献求助收藏

The Flagellin-Specific Chaperone FliS of Borrelia burgdorferi Controls the Cytoplasmic Pool of Flagellins at the Level of Translation Initiation, Secretion, and Proteolysis

伯氏疏螺旋体鞭毛蛋白特异性分子伴侣FliS在翻译起始、分泌和蛋白水解水平上调控细胞质鞭毛蛋白库。

期刊:Molecular Microbiology

影响因子:2.6

doi:10.1111/mmi.15380

Sze, Ching Wooen; Zhang, Kai; Lynch, Michael J; Guo, Wangbiao; Liu, Jun; Crane, Brian R; Li, Chunhao

Lactate dehydrogenase is the Achilles' heel of Lyme disease bacterium Borreliella burgdorferi

乳酸脱氢酶是莱姆病病原体伯氏疏螺旋体的阿喀琉斯之踵。

期刊:

影响因子:

doi:10.1101/2025.02.07.637162

Sze, Ching Wooen; Lynch, Michael J; Zhang, Kai; Neau, David B; Ealick, Steven E; Crane, Brian R; Li, Chunhao

MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi

MCP5是一种甲基受体趋化蛋白，受Hk1-Rrp1和Rrp2-RpoN-RpoS通路调控，是伯氏疏螺旋体逃避免疫所必需的。

期刊:PLoS Pathogens

影响因子:5.5

doi:10.1371/journal.ppat.1012327

Sajith Raghunandanan ，Kai Zhang ，Yan Zhang ，Raj Priya ，Ching Wooen Sze ，Yongliang Lou ，Michael J Lynch ，Brian R Crane ，Mark H Kaplan ，Chunhao Li ，X Frank Yang

A pleiotropic role of sialidase in the pathogenicity of Porphyromonas gingivalis

唾液酸酶在牙龈卟啉单胞菌致病性中的多效性作用

期刊:Infection and Immunity

影响因子:2.9

doi:10.1128/iai.00344-23

Christopher Pham,Shuaiqi Guo,Xiao Han,Laurynn Coleman,Ching Wooen Sze,Huizhi Wang,Jun Liu,Chunhao Li

发表日期：2024

文献求助收藏

MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi

MCP5是一种甲基受体趋化蛋白，受Hk1-Rrp1和Rrp2-RpoN-RpoS通路调控，是伯氏疏螺旋体逃避免疫所必需的。

期刊:

影响因子:

doi:10.1101/2024.06.10.598185

Raghunandanan, Sajith; Zhang, Kai; Zhang, Yan; Sze, Ching Wooen; Priya, Raj; Luo, Yongliang; Lynch, Michael J; Crane, Brian R; Li, Chunhao; Yang, X Frank

Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors

功能和结构分析表明，双域唾液酸酶通过补体因子的脱唾液酸化保护细菌免受补体杀伤

期刊:PLoS Pathogens

影响因子:5.5

doi:10.1371/journal.ppat.1011674

Nicholas D Clark, Christopher Pham, Kurni Kurniyati, Ching Wooen Sze, Laurynn Coleman, Qin Fu, Sheng Zhang, Michael G Malkowski, Chunhao Li

微生物学

发表日期：2023

文献求助收藏

A chemosensory-like histidine kinase is dispensable for chemotaxis in vitro but regulates the virulence of Borrelia burgdorferi through modulating the stability of RpoS

一种类似化学感受器的组氨酸激酶在体外趋化作用中并非必需，但它通过调节RpoS的稳定性来调控伯氏疏螺旋体的毒力。

期刊:PLoS Pathogens

影响因子:4.9

doi:10.1371/journal.ppat.1011752

Sze, Ching Wooen; Zhang, Kai; Lynch, Michael J; Iyer, Radha; Crane, Brian R; Schwartz, Ira; Li, Chunhao

信号转导

发表日期：2023

文献求助收藏

A bipartite bacterial virulence factor targets the complement system and neutrophil activation

一种双组分细菌毒力因子靶向补体系统和中性粒细胞活化。

Borrelia burgdorferi serine protease HtrA is a pleiotropic regulator of stress response, motility, flagellar hemostasis, and infectivity

伯氏疏螺旋体丝氨酸蛋白酶HtrA是应激反应、运动性、鞭毛止血和感染性的多效性调节因子。

Lactate dehydrogenase is the Achilles' heel of Lyme disease bacterium Borreliella burgdorferi.

乳酸脱氢酶是莱姆病细菌伯氏疏螺旋体的阿喀琉斯之踵

The Flagellin-Specific Chaperone FliS of Borrelia burgdorferi Controls the Cytoplasmic Pool of Flagellins at the Level of Translation Initiation, Secretion, and Proteolysis

伯氏疏螺旋体鞭毛蛋白特异性分子伴侣FliS在翻译起始、分泌和蛋白水解水平上调控细胞质鞭毛蛋白库。

Lactate dehydrogenase is the Achilles' heel of Lyme disease bacterium Borreliella burgdorferi

乳酸脱氢酶是莱姆病病原体伯氏疏螺旋体的阿喀琉斯之踵。

MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi

MCP5是一种甲基受体趋化蛋白，受Hk1-Rrp1和Rrp2-RpoN-RpoS通路调控，是伯氏疏螺旋体逃避免疫所必需的。

A pleiotropic role of sialidase in the pathogenicity of Porphyromonas gingivalis

唾液酸酶在牙龈卟啉单胞菌致病性中的多效性作用

MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi

MCP5是一种甲基受体趋化蛋白，受Hk1-Rrp1和Rrp2-RpoN-RpoS通路调控，是伯氏疏螺旋体逃避免疫所必需的。

Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors

功能和结构分析表明，双域唾液酸酶通过补体因子的脱唾液酸化保护细菌免受补体杀伤

A chemosensory-like histidine kinase is dispensable for chemotaxis in vitro but regulates the virulence of Borrelia burgdorferi through modulating the stability of RpoS

一种类似化学感受器的组氨酸激酶在体外趋化作用中并非必需，但它通过调节RpoS的稳定性来调控伯氏疏螺旋体的毒力。