日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus

对高等灵长类动物抗登革病毒抗体中和机制的结构性见解

Cockburn, Joseph J B; Navarro Sanchez, M Erika; Goncalvez, Ana P; Zaitseva, Elena; Stura, Enrico A; Kikuti, Carlos M; Duquerroy, Stéphane; Dussart, Philippe; Chernomordik, Leonid V; Lai, Ching-Juh; Rey, Felix A

Passage of dengue virus type 4 vaccine candidates in fetal rhesus lung cells selects heparin-sensitive variants that result in loss of infectivity and immunogenicity in rhesus macaques.

登革病毒 4 型候选疫苗在恒河猴胎儿肺细胞中进行传代培养,筛选出对肝素敏感的变异株,导致恒河猴丧失感染性和免疫原性

Añez Germán, Men Ruhe, Eckels Kenneth H, Lai Ching-Juh

Dengue virus neutralization is modulated by IgG antibody subclass and Fcgamma receptor subtype

登革病毒中和作用受IgG抗体亚类和Fcγ受体亚型的调节。

Rodrigo, W W Shanaka I; Block, Olivia K T; Lane, Christopher; Sukupolvi-Petty, Soila; Goncalvez, Ana P; Johnson, Syd; Diamond, Michael S; Lai, Ching-Juh; Rose, Robert C; Jin, Xia; Schlesinger, Jacob J

Humanized monoclonal antibodies derived from chimpanzee Fabs protect against Japanese encephalitis virus in vitro and in vivo

来自黑猩猩 Fab 的人源化单克隆抗体可在体内和体外抵抗日本脑炎病毒

Ana P Goncalvez, Cheng-Hsin Chien, Kamolchanok Tubthong, Inna Gorshkova, Carrie Roll, Olivia Donau, Peter Schuck, Sutee Yoksan, Sy-Dar Wang, Robert H Purcell, Ching-Juh Lai

Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention.

单克隆抗体介导的登革病毒感染在体外和体内的增强及其预防策略

Goncalvez Ana P, Engle Ronald E, St Claire Marisa, Purcell Robert H, Lai Ching-Juh