日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Orally Bioavailable and Site-Selective Covalent STING Inhibitor Derived from a Macrocyclic Marine Diterpenoid

一种源自大环海洋二萜类化合物的口服生物利用度高且具有位点选择性的共价STING抑制剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c02665
Guang-Hao Niu ,Wan-Chi Hsiao ,Po-Hsun Lee ,Li-Guo Zheng ,Yu-Shao Yang ,Wei-Cheng Huang ,Chih-Chien Hsieh ,Tai-Yu Chiu ,Jing-Ya Wang ,Ching-Ping Chen ,Chen-Lung Huang ,May-Su You ,Yi-Ping Kuo ,Chien-Ming Wang ,Zhi-Hong Wen ,Guann-Yi Yu ,Chiung-Tong Chen ,Ya-Hui Chi ,Chun-Wei Tung ,Shu-Ching Hsu ,Teng-Kuang Yeh ,Ping-Jyun Sung ,Mingzi M Zhang ,Lun Kelvin Tsou
STING
发表日期：2025
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Simvastatin Attenuates Areca Nut Extract-Induced Subdermal Fibrosis in Mice by Targeting TGF-β Signaling Pathways

辛伐他汀通过靶向TGF-β信号通路减轻槟榔提取物诱导的小鼠皮下纤维化

期刊:Current Issues in Molecular Biology
影响因子:3
doi:10.3390/cimb45110542
Chang, Chi-Hua; Lin, Ching-Ping; Chen, Yuk-Kwan; Hsiao, Yu-Fang; Wang, Yan-Hsiung
TGF-β
信号转导
发表日期：2023
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Serological Responses and Predictive Factors of Booster COVID-19 Vaccines in Patients with Hematologic Malignancies

血液系统恶性肿瘤患者接种新冠加强疫苗的血清学反应及预测因素

期刊:Journal of Clinical Medicine
影响因子:2.9
doi:10.3390/jcm12175647
Huang, Chien-Tzu; Lee, Ching-Ping; Chen, Tzu-Yin; Liu, Yi-Chang; Cho, Shih-Feng; Du, Jeng-Shiun; Yu, Ming-Lung; Huang, Chung-Feng; Wang, Sheng-Fan; Hsiao, Hui-Hua
新冠
肿瘤
肿瘤免疫
微生物学
发表日期：2023
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Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins

发现并合成基于嘧啶的 Aurora 激酶抑制剂以降低 MYC 癌蛋白的水平

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.0c01806
Ya-Hui Chi, Teng-Kuang Yeh, Yi-Yu Ke, Wen-Hsing Lin, Chia-Hua Tsai, Wan-Ping Wang, Yen-Ting Chen, Yu-Chieh Su, Pei-Chen Wang, Yan-Fu Chen, Zhong-Wei Wu, Jen-Yu Yeh, Ming-Chun Hung, Mine-Hsine Wu, Jing-Ya Wang, Ching-Ping Chen, Jen-Shin Song, Chuan Shih, Chiung-Tong Chen, Chun-Ping Chang
肿瘤
WB
发表日期：2021
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BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy

BPRDP056，一种专门针对磷脂酰丝氨酸的新型小分子药物偶联物，用于癌症治疗

期刊:Translational Oncology
影响因子:4.5
doi:10.1016/j.tranon.2020.100897
Yun-Yu Chen, Chen-Fu Lo, Tai-Yu Chiu, Chia-Yu Hsu, Teng-Kuang Yeh, Ching-Ping Chen, Chen-Lung Huang, Chung-Yu Huang, Min-Hsien Wang, Yu-Chen Huang, Hsuan-Hui Ho, Yu-Sheng Chao, Joe C Shih, Lun K Tsou, Chiung-Tong Chen
肿瘤
发表日期：2021
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Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System

脂肪乳对纳米药物 Abraxane 疗法和先天免疫系统的影响

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-020-59813-7
Yen-Ju Chen #, Chin-Yi Tsai #, Ying-Min Cheng, Su-Wen Nieh, Teng-Kuang Yeh, Ching- Ping Chen, Min-Hsien Wang, Ling-Hui Chou, Tai-Yu Chiu, Li Liu, Chien Ho, Chiung- Tong Chen, Tsang-Wu Liu
免疫
发表日期：2020
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Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation

发现用于治疗 AML 和实体肿瘤的喹唑啉类多激酶抑制剂 BPR1K871：合理设计、合成、体外和体内评估

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.13369
Yung Chang Hsu, Mohane Selvaraj Coumar, Wen-Chieh Wang, Hui-Yi Shiao, Yi-Yu Ke, Wen-Hsing Lin, Ching-Chuan Kuo, Chun-Wei Chang, Fu-Ming Kuo, Pei-Yi Chen, Sing-Yi Wang, An-Siou Li, Chun-Hwa Chen, Po-Chu Kuo, Ching-Ping Chen, Ming-Hsine Wu, Chen-Lung Huang, Kuei-Jung Yen, Yun-I Chang, John T-A Hsu, Ch
肿瘤
WB
发表日期：2016
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Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer

评估 BPR1J-340（一种强效选择性 FLT3 抑制剂）单独使用或与 HDAC 抑制剂伏立诺他联合使用对 AML 癌症的抗肿瘤作用

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0083160
Wen-Hsing Lin, Teng-Kuang Yeh, Weir-Torn Jiaang, Kuei-Jung Yen, Chun-Hwa Chen, Chin-Ting Huang, Shih-Chieh Yen, Shu-Yi Hsieh, Ling-Hui Chou, Ching-Ping Chen, Chun-Hsien Chiu, Li-Chun Kao, Yu-Sheng Chao, Chiung-Tong Chen, John T-A Hsu
肿瘤
发表日期：2014
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Characterization of Niemann-Pick Type C2 protein expression in multiple cancers using a novel NPC2 monoclonal antibody

利用新型NPC2单克隆抗体对多种癌症中尼曼-匹克C型蛋白的表达进行表征

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0077586
Liao, Yi-Jen; Lin, Meng-Wei; Yen, Chia-Hung; Lin, Yu-Ting; Wang, Chung-Kwe; Huang, Shiu-Feng; Chen, Kuan-Hsuan; Yang, Ching-Ping; Chen, Tzu-Lang; Hou, Ming-Feng; Arthur Chen, Yi-Ming
单克隆抗体
肿瘤
肿瘤免疫
发表日期：2013
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Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules

Aurora 激酶抑制剂揭示 HURP 在着丝粒和着丝粒微管成核中的机制

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.1220523110
Jiun-Ming Wu, Chiung-Tong Chen, Mohane Selvaraj Coumar, Wen-Hsin Lin, Zi-Jie Chen, John T-A Hsu, Yi-Hui Peng, Hui-Yi Shiao, Wen-Hsing Lin, Chang-Ying Chu, Jian-Sung Wu, Chih-Tsung Lin, Ching-Ping Chen, Ching-Cheng Hsueh, Kai-Yen Chang, Li-Pin Kao, Chi-Ying F Huang, Yu-Sheng Chao, Su-Ying Wu, Hsing-P
信号转导
IP
WB
Human
发表日期：2013
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