日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A novel long-galanin peptide from non-mammalian vertebrates mitigates the inflammatory response in IBD models via the biased GALR2/β-arrestin2 pathway

一种来自非哺乳动物脊椎动物的新型长链加兰素肽可通过偏向性GALR2/β-arrestin2通路减轻IBD模型中的炎症反应。

Lai, Shanshan; Kong, Xianglin; Xue, Jingwen; Ma, Kaili; Amanullah, Amanullah; Chen, Yuwei; Yang, Na; Zhang, Ting; Zheng, Kun; Zeng, Tao; Yan, Xiaofei; Zhang, Chang; Kamal, Shah; Ullah, Najeeb; Luo, Chingwei; Brosius, Juergen; Deng, Cheng

Trop-2 expression in non-small cell lung cancer.

非小细胞肺癌中Trop-2的表达

Kuo Peiwen, Elboudwarej Emon, Zavodovskaya Marianna, Lin Kai-Wen, Lee Chingwei V, Diehl Lauri, Patel Jilpa, Mekan Sabeen, Jürgensmeier Juliane M

Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy

治疗性抗 HtrA1 抗体的开发以及 DKK3 被鉴定为地图样萎缩的药效学生物标志物

Irene Tom, Victoria C Pham, Kenneth J Katschke Jr, Wei Li, Wei-Ching Liang, Johnny Gutierrez, Andrew Ah Young, Isabel Figueroa, Shadi Toghi Eshghi, ChingWei V Lee, Jitendra Kanodia, Scott J Snipas, Guy S Salvesen, Phillip Lai, Lee Honigberg, Menno van Lookeren Campagne, Daniel Kirchhofer, Amos Baruc

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

通过 ITV 非选择性 ANGPT 1/2 抗体快速发展青光眼:ANGPT/TIE2 信号在灵长类房水流出中的潜在作用

Evan A Thackaberry, Yi Zhou, Christina L Zuch de Zafra, Germaine Fuh, Chingwei V Lee, Sarah Sanowar, John B Ridgway, Aija M Kusi, Cindy Farman, Helen Booler, Daniel Sheinson, Carol A Rasmussen, Paul E Miller, Eric Wakshull, Minhong Yan, Vladimir Bantseev

Tuning the specificity of a Two-in-One Fab against three angiogenic antigens by fully utilizing the information of deep mutational scanning

充分利用深度突变扫描的信息来调整二合一 Fab 针对三种血管生成抗原的特异性

Patrick Koenig, Sarah Sanowar, Chingwei V Lee, Germaine Fuh

Mutational landscape of antibody variable domains reveals a switch modulating the interdomain conformational dynamics and antigen binding

抗体可变结构域的突变景观揭示了调节域间构象动力学和抗原结合的开关

Patrick Koenig, Chingwei V Lee, Benjamin T Walters, Vasantharajan Janakiraman, Jeremy Stinson, Thomas W Patapoff, Germaine Fuh

Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration

深度测序指导设计高亲和力双特异性抗体以靶向新生血管性年龄相关性黄斑变性中的两种血管生成因子

Patrick Koenig, Chingwei V Lee, Sarah Sanowar, Ping Wu, Jeremy Stinson, Seth F Harris, Germaine Fuh

A two-in-one antibody engineered from a humanized interleukin 4 antibody through mutation in heavy chain complementarity-determining regions

通过重链互补决定区突变,由人源化白细胞介素 4 抗体改造而成的二合一抗体

Chingwei V Lee, Patrick Koenig, Germaine Fuh

Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasis

VEGF-C 抑制调节远端淋巴管重塑和继发性转移

Alvin Gogineni, Maresa Caunt, Ailey Crow, Chingwei V Lee, Germaine Fuh, Nicholas van Bruggen, Weilan Ye, Robby M Weimer

Translation levels control multi-spanning membrane protein expression.

翻译水平控制着跨膜蛋白的表达

Kim Hok Seon, Ernst James A, Brown Cecilia, Bostrom Jenny, Fuh Germaine, Lee Chingwei V, Huang Arthur, Vandlen Richard L, Yansura Daniel G