日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Simulation-based evaluation of personalized dosing approaches for anti-FGFR/KLB bispecific antibody fazpilodemab

基于模拟的抗FGFR/KLB双特异性抗体法匹洛单抗个体化给药方案评估

Yoshida, Kenta; Poon, Victor; Dash, Ajit; Kunder, Rebecca; Chinn, Leslie; Kågedal, Matts

Fenebrutinib versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double-Blind, Phase II Trial (ANDES Study)

芬布替尼与安慰剂或阿达木单抗治疗类风湿性关节炎:一项随机、双盲、II期试验(ANDES研究)

Cohen, Stanley; Tuckwell, Katie; Katsumoto, Tamiko R; Zhao, Rui; Galanter, Joshua; Lee, Chin; Rae, Julie; Toth, Balazs; Ramamoorthi, Nandhini; Hackney, Jason A; Berman, Alberto; Damjanov, Nemanja; Fedkov, Dmytro; Jeka, Slawomir; Chinn, Leslie W; Townsend, Michael J; Morimoto, Alyssa M; Genovese, Mark C

Antibody-mediated activation of the FGFR1/Klothoβ complex corrects metabolic dysfunction and alters food preference in obese humans

抗体介导的FGFR1/Klothoβ复合物激活可纠正肥胖人群的代谢功能障碍并改变其食物偏好。

Baruch, Amos; Wong, Chin; Chinn, Leslie W; Vaze, Anjali; Sonoda, Junichiro; Gelzleichter, Thomas; Chen, Shan; Lewin-Koh, Nicholas; Morrow, Linda; Dheerendra, Suresh; Boismenu, Richard; Gutierrez, Johnny; Wakshull, Eric; Wilson, Maria E; Arora, Puneet S

Understanding the Effect of Hydroxypropyl-β-Cyclodextrin on Fenebrutinib Absorption in an Itraconazole-Fenebrutinib Drug-Drug Interaction Study

了解羟丙基-β-环糊精对伊曲康唑-非那替尼药物相互作用研究中非那替尼吸收的影响

Durk, Matthew R; Jones, Nicholas S; Liu, Jia; Nagapudi, Karthik; Mao, Chen; Plise, Emile G; Wong, Susan; Chen, Jacob Z; Chen, Yuan; Chinn, Leslie W; Chiang, Po-Chang

Physiologically-Based Pharmacokinetic Model-Informed Drug Development for Fenebrutinib: Understanding Complex Drug-Drug Interactions

基于生理药代动力学模型指导的芬布替尼药物开发:理解复杂的药物相互作用

Chen, Yuan; Ma, Fang; Jones, Nicholas S; Yoshida, Kenta; Chiang, Po-Chang; Durk, Matthew R; Wright, Matthew R; Jin, Jin Yan; Chinn, Leslie W

Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)

非常重要的药理基因概述:ABCB1(MDR1,P-糖蛋白)

Hodges, Laura M; Markova, Svetlana M; Chinn, Leslie W; Gow, Jason M; Kroetz, Deanna L; Klein, Teri E; Altman, Russ B

Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila.

果蝇中脊椎动物血脑屏障化学保护机制的进化保守性

Mayer Fahima, Mayer Nasima, Chinn Leslie, Pinsonneault Robert L, Kroetz Deanna, Bainton Roland J