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Underestimation of mitochondrial respiratory capacity in gray matter voxels of the human brain map due to limited OXPHOS and TCA cycle in astrocytes

由于星形胶质细胞中氧化磷酸化和三羧酸循环的局限性，导致人脑图谱灰质体素中线粒体呼吸能力被低估。

期刊:Frontiers in Cellular Neuroscience

影响因子:4

doi:10.3389/fncel.2025.1661231

Chinopoulos, Christos

The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer

瓦尔堡假说与线粒体代谢癌症理论的出现

期刊:Journal of Bioenergetics and Biomembranes

影响因子:3

doi:10.1007/s10863-025-10059-w

Seyfried, Thomas N; Lee, Derek C; Duraj, Tomas; Ta, Nathan L; Mukherjee, Purna; Kiebish, Michael; Arismendi-Morillo, Gabriel; Chinopoulos, Christos

Reverse phase protein array-based investigation of mitochondrial genes reveals alteration of glutaminolysis in the parahippocampal cortex of people who died by suicide

基于反相蛋白阵列的线粒体基因研究揭示了自杀身亡者海马旁皮质谷氨酰胺分解的改变

期刊:Translational Psychiatry

影响因子:5.8

doi:10.1038/s41398-024-03137-x

Fanni Dóra, Tamara Hajdu, Éva Renner, Krisztina Paál, Alán Alpár, Miklós Palkovits, Christos Chinopoulos, Arpád Dobolyi

Cell-specific expression of key mitochondrial enzymes limits OXPHOS in astrocytes of the adult human neocortex and hippocampal formation

关键线粒体酶的细胞特异性表达限制了成人人类新皮质和海马结构星形胶质细胞中的 OXPHOS

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-024-06751-z

Arpád Dobolyi, Melinda Cservenák, Attila G Bagó, Chun Chen, Anna Stepanova, Krisztina Paal, Jeonghyoun Lee, Miklós Palkovits, Gavin Hudson, Christos Chinopoulos

Complex I activity in hypoxia: implications for oncometabolism

缺氧条件下复合物I活性：对肿瘤代谢的影响

期刊:Biochemical Society Transactions

影响因子:4.3

doi:10.1042/BST20230189

Chinopoulos, Christos

Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells.

氨基酸和葡萄糖发酵维持小鼠和人类恶性胶质瘤细胞中的 ATP 含量

期刊:ASN Neuro

影响因子:3.7

doi:10.1080/17590914.2024.2422268

Lee Derek C, Ta Linh, Mukherjee Purna, Duraj Tomas, Domin Marek, Greenwood Bennett, Karmacharya Srada, Narain Niven R, Kiebish Michael, Chinopoulos Christos, Seyfried Thomas N

Viability of HepG2 and MCF-7 cells is not correlated with mitochondrial bioenergetics

HepG2 和 MCF-7 细胞活力与线粒体生物能量学无关

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-023-37677-x

Judit Doczi, Noemi Karnok, David Bui, Victoria Azarov, Gergely Pallag, Sara Nazarian, Bence Czumbel, Thomas N Seyfried, Christos Chinopoulos

Reverse and Forward Electron Flow-Induced H(2)O(2) Formation Is Decreased in α-Ketoglutarate Dehydrogenase (α-KGDH) Subunit (E2 or E3) Heterozygote Knock Out Animals

在α-酮戊二酸脱氢酶（α-KGDH）亚基（E2或E3）杂合敲除动物中，反向和正向电子流诱导的H(2)O(2)生成减少

期刊:Antioxidants

影响因子:6.6

doi:10.3390/antiox11081487

Horváth, Gergő; Sváb, Gergely; Komlódi, Tímea; Ravasz, Dora; Kacsó, Gergely; Doczi, Judit; Chinopoulos, Christos; Ambrus, Attila; Tretter, László

发表日期：2022

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Proline Oxidation Supports Mitochondrial ATP Production When Complex I Is Inhibited

当复合物I受到抑制时，脯氨酸氧化可支持线粒体ATP的产生。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms23095111

Pallag, Gergely; Nazarian, Sara; Ravasz, Dora; Bui, David; Komlódi, Timea; Doerrier, Carolina; Gnaiger, Erich; Seyfried, Thomas N; Chinopoulos, Christos

线粒体

发表日期：2022

文献求助收藏

Catabolic rewiring in cancer impacts dietary interventions

癌症中的分解代谢重编程会影响饮食干预

Underestimation of mitochondrial respiratory capacity in gray matter voxels of the human brain map due to limited OXPHOS and TCA cycle in astrocytes

由于星形胶质细胞中氧化磷酸化和三羧酸循环的局限性，导致人脑图谱灰质体素中线粒体呼吸能力被低估。

The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer

瓦尔堡假说与线粒体代谢癌症理论的出现

Reverse phase protein array-based investigation of mitochondrial genes reveals alteration of glutaminolysis in the parahippocampal cortex of people who died by suicide

基于反相蛋白阵列的线粒体基因研究揭示了自杀身亡者海马旁皮质谷氨酰胺分解的改变

Cell-specific expression of key mitochondrial enzymes limits OXPHOS in astrocytes of the adult human neocortex and hippocampal formation

关键线粒体酶的细胞特异性表达限制了成人人类新皮质和海马结构星形胶质细胞中的 OXPHOS

Complex I activity in hypoxia: implications for oncometabolism

缺氧条件下复合物I活性：对肿瘤代谢的影响

Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells.

氨基酸和葡萄糖发酵维持小鼠和人类恶性胶质瘤细胞中的 ATP 含量

Viability of HepG2 and MCF-7 cells is not correlated with mitochondrial bioenergetics

HepG2 和 MCF-7 细胞活力与线粒体生物能量学无关

Reverse and Forward Electron Flow-Induced H(2)O(2) Formation Is Decreased in α-Ketoglutarate Dehydrogenase (α-KGDH) Subunit (E2 or E3) Heterozygote Knock Out Animals

在α-酮戊二酸脱氢酶（α-KGDH）亚基（E2或E3）杂合敲除动物中，反向和正向电子流诱导的H(2)O(2)生成减少

Proline Oxidation Supports Mitochondrial ATP Production When Complex I Is Inhibited

当复合物I受到抑制时，脯氨酸氧化可支持线粒体ATP的产生。