Design, Synthesis, and Investigation of the Pharmacokinetics and Anticancer Activities of Indenoisoquinoline Derivatives That Stabilize the G-Quadruplex in the MYC Promoter and Inhibit Topoisomerase I.
设计、合成和研究稳定 MYC 启动子中 G-四链体并抑制拓扑异构酶 I 的茚并异喹啉衍生物的药代动力学和抗癌活性
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.3c02303
Han Yichen, Buric Adam, Chintareddy Venkat, DeMoss Mercedes, Chen Luying, Dickerhoff Jonathan, De Dios Robyn, Chand Pooran, Riggs Randall, Yang Danzhou, Cushman Mark
