Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models
单甲基奥瑞他汀 E 与抗 CD30 抗体的位点特异性结合可改善其在啮齿动物模型中的药代动力学和治疗指数
期刊:Molecular Pharmaceutics
影响因子:3.2
doi:10.1021/mp500666j
F Lhospice, D Brégeon, C Belmant, P Dennler, A Chiotellis, E Fischer, L Gauthier, A Boëdec, H Rispaud, S Savard-Chambard, A Represa, N Schneider, C Paturel, M Sapet, C Delcambre, S Ingoure, N Viaud, C Bonnafous, R Schibli, F Romagné