日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cholesterol-conjugated miR-29b induces fetal haemoglobin expression via γ-globin promoter demethylation in the Townes mouse model for sickle cell anaemia

在镰状细胞贫血症的Townes小鼠模型中,胆固醇结合的miR-29b通过γ-珠蛋白启动子去甲基化诱导胎儿血红蛋白表达。

Chithra D Palani ,Alana Smith ,Xueyuan Cao ,Biaoru Li ,Betty S Pace ,Athena Starlard-Davenport

Innovations in Drug Discovery for Sickle Cell Disease Targeting Oxidative Stress and NRF2 Activation-A Short Review

镰状细胞病药物研发创新:靶向氧化应激和NRF2激活——简要综述

Starlard-Davenport, Athena; Palani, Chithra D; Zhu, Xingguo; Pace, Betty S

Bach1 inhibitor HPP-D mediates γ-globin gene activation in sickle erythroid progenitors

Bach1抑制剂HPP-D介导镰状红系祖细胞中γ-珠蛋白基因的激活

Chithra D Palani ,Xingguo Zhu ,Manickam Alagar ,Otis C Attucks ,Betty S Pace

MicroRNA29B induces fetal hemoglobin via inhibition of the HBG repressor protein MYB in vitro and in humanized sickle cell mice

MicroRNA29B 通过抑制 HBG 抑制蛋白 MYB(体外和人源化镰状细胞小鼠)诱导胎儿血红蛋白

Qingqing Gu, Chithra D Palani, Alana Smith, Biaori Li, Ernestine Kubi Amos-Abanyie, Ugochi Ogu, Lu Lu, Betty S Pace, Athena Starlard-Davenport

Deletion of arginase 2 attenuates neuroinflammation in an experimental model of optic neuritis

在视神经炎的实验模型中,精氨酸酶2的缺失可减轻神经炎症。

Amritha A Candadai ,Fang Liu ,Abdelrahman Y Fouda ,Moaddey Alfarhan ,Chithra D Palani ,Zhimin Xu ,Ruth B Caldwell ,S Priya Narayanan

Deletion of Arginase 2 Ameliorates Retinal Neurodegeneration in a Mouse Model of Multiple Sclerosis

精氨酸酶2的缺失可改善多发性硬化症小鼠模型中的视网膜神经退行性变

Chithra D Palani ,Abdelrahman Y Fouda ,Fang Liu ,Zhimin Xu ,Eslam Mohamed ,Shailedra Giri ,Sylvia B Smith ,Ruth B Caldwell ,S Priya Narayanan

Cytotoxicity and osteogenic potential of silicate calcium cements as potential protective materials for pulpal revascularization

硅酸钙水泥作为牙髓血管重建潜在保护材料的细胞毒性和成骨潜能

Bortoluzzi, Eduardo A; Niu, Li-Na; Palani, Chithra D; El-Awady, Ahmed R; Hammond, Barry D; Pei, Dan-Dan; Tian, Fu-Cong; Cutler, Christopher W; Pashley, David H; Tay, Franklin R

Porphyromonas gingivalis evasion of autophagy and intracellular killing by human myeloid dendritic cells involves DC-SIGN-TLR2 crosstalk

牙龈卟啉单胞菌逃避人类髓系树突状细胞的自噬和细胞内杀伤涉及 DC-SIGN-TLR2 串扰

Ahmed R El-Awady, Brodie Miles, Elizabeth Scisci, Zoya B Kurago, Chithra D Palani, Roger M Arce, Jennifer L Waller, Caroline A Genco, Connie Slocum, Matthew Manning, Patricia V Schoenlein, Christopher W Cutler

Histone deacetylase inhibitor-mediated sensitization to TRAIL-induced apoptosis in childhood malignancies is not associated with upregulation of TRAIL receptor expression, but with potentiated caspase-8 activation

组蛋白去乙酰化酶抑制剂介导的对儿童恶性肿瘤中 TRAIL 诱导的细胞凋亡的敏感性与 TRAIL 受体表达的上调无关,但与增强的 caspase-8 活化有关

Jürgen Sonnemann, Navina Trommer, Sabine Becker, Susan Wittig, Désirée Grauel, Chithra D Palani, James F Beck

Histone deacetylase inhibitors induce cell death and enhance the apoptosis-inducing activity of TRAIL in Ewing's sarcoma cells

组蛋白去乙酰化酶抑制剂可诱导尤文氏肉瘤细胞死亡,并增强TRAIL的促凋亡活性。

Sonnemann, Jürgen; Dreyer, Linn; Hartwig, Maite; Palani, Chithra D; Hong, Le Thi Thu; Klier, Ulrike; Bröker, Barbara; Völker, Uwe; Beck, James F