日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chemical and genetic rescue of in vivo progranulin-deficient lysosomal and autophagic defects

化学和基因方法可挽救体内前粒蛋白缺陷引起的溶酶体和自噬缺陷。

Doyle, James J; Maios, Claudia; Vrancx, Céline; Duhaime, Sarah; Chitramuthu, Babykumari; Bennett, Hugh P J; Bateman, Andrew; Parker, J Alex

Multiple Molecular Pathways Are Influenced by Progranulin in a Neuronal Cell Model-A Parallel Omics Approach

在神经元细胞模型中,前粒蛋白影响多种分子通路——一种平行组学方法

Chitramuthu, Babykumari P; Campos-García, Víctor R; Bateman, Andrew

Structure dissection of zebrafish progranulins identifies a well-folded granulin/epithelin module protein with pro-cell survival activities

斑马鱼前粒蛋白的结构解析鉴定出一种折叠良好的粒蛋白/上皮蛋白模块蛋白,该蛋白具有促进细胞存活的活性。

Wang, Ping; Chitramuthu, Babykumari; Bateman, Andrew; Bennett, Hugh P J; Xu, Ping; Ni, Feng

Neurotrophic effects of progranulin in vivo in reversing motor neuron defects caused by over or under expression of TDP-43 or FUS

体内前粒蛋白的神经营养作用可逆转由TDP-43或FUS过度表达或表达不足引起的运动神经元缺陷

Chitramuthu, Babykumari P; Kay, Denis G; Bateman, Andrew; Bennett, Hugh P J

High resolution whole mount in situ hybridization within zebrafish embryos to study gene expression and function

利用斑马鱼胚胎高分辨率原位杂交技术研究基因表达和功能

Chitramuthu, Babykumari P; Bennett, Hugh P J

Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1

前颗粒蛋白调节斑马鱼体内运动神经元的发育并挽救与生存运动神经元 1 敲除相关的截断缺陷

Babykumari P Chitramuthu, David C Baranowski, Denis G Kay, Andrew Bateman, Hugh Pj Bennett

Progranulin is expressed within motor neurons and promotes neuronal cell survival.

前粒蛋白在运动神经元内表达,并促进神经元细胞存活

Ryan Cara L, Baranowski David C, Chitramuthu Babykumari P, Malik Suneil, Li Zhi, Cao Mingju, Minotti Sandra, Durham Heather D, Kay Denis G, Shaw Christopher A, Bennett Hugh P J, Bateman Andrew

The zebrafish progranulin gene family and antisense transcripts

斑马鱼前粒蛋白基因家族和反义转录本

Cadieux, Benoît; Chitramuthu, Babykumari P; Baranowski, David; Bennett, Hugh P J