Chiu Mark L相关文献与解析，生知库 | 链接生命科学的每一步

A Bispecific Antibody Blocking Both TSLP and IL-4Rα for the Treatment of Allergic Inflammatory Diseases

双特异性抗体阻断TSLP和IL-4Rα治疗过敏性炎症疾病

期刊:Cells

影响因子:5.2

doi:10.3390/cells14221747

Yu, Mingcan; Chen, Peng; Jin, Ying; Huang, Sheng; Jiang, Hao; Zhou, Fulai; Chiu, Mark L; Zhang, Di

Targeted Hyaluronan Degradation Enhanced Tumor Growth Inhibition in Gastrointestinal Cancer Models.

靶向透明质酸降解增强了胃肠道癌症模型中的肿瘤生长抑制作用。

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers17213411

Zhou Fulai, Mu Guangmao, Bi Honglei, Chen Limin, Zha Zhengxia, Jin Ying, Chiu Mark L

Discovery and Phase 1 study of a novel monoclonal antibody against human IL-1β for the treatment of IL-1β-mediated diseases

针对人IL-1β的新型单克隆抗体的发现和I期研究，用于治疗IL-1β介导的疾病

期刊:Clinical and Experimental Immunology

影响因子:3.8

doi:10.1093/cei/uxaf009

Cho, Minseon; Tam, Susan H; Shi, Lihua; Fung, Isa; Tornetta, Mark; Canziani, Gabriela A; Fung, Man-Cheong; Chiu, Mark L; Han, Chao; Zhang, Di

A trispecific antibody targeting EGFR/cMET/VEGF-A demonstrates multiple mechanisms of action to inhibit wild-type and mutant NSCLC animal models.

针对 EGFR/cMET/VEGF-A 的三特异性抗体表现出多种作用机制，可抑制野生型和突变型 NSCLC 动物模型

期刊:Frontiers in Oncology

影响因子:3.3

doi:10.3389/fonc.2025.1533059

Jin Ying, Sun Ping, Chen Peng, Xu Yuqiang, Mu Guangmao, Zha Zhengxia, Wu Simin, Fu Meixia, Jiang Hao, Huang Sheng, Zhou Fulai, Han Chao, Chiu Mark L

Guidelines in the Preparation of Fully Synthetic, Human Single-Domain Antibody Phage Display Libraries.

全合成人源单域抗体噬菌体展示文库的制备指南

期刊:Antibodies

影响因子:2.7

doi:10.3390/antib14030071

Tornetta Mark A, Whitaker Brian P, Cantwell Olivia M, Haytko Peter N, Pisors Eileen D, Zhou Fulai, Chiu Mark L

A novel monoclonal antibody against human thymic stromal lymphopoietin for the treatment of TSLP-mediated diseases

一种新型抗人胸腺基质淋巴细胞生成素单克隆抗体，用于治疗TSLP介导的疾病

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2024.1442588

Shi, Lihua; Yu, Mingcan; Jin, Ying; Chen, Peng; Mu, Guangmao; Tam, Susan H; Cho, Minseon; Tornetta, Mark; Han, Chao; Fung, Man-Cheong; Chiu, Mark L; Zhang, Di

The process using a synthetic library that generates multiple diverse human single domain antibodies.

该方法利用合成文库生成多种不同的人类单域抗体

期刊:Antibody Therapeutics

影响因子:4.5

doi:10.1093/abt/tbae020

Tornetta Mark A, Whitaker Brian P, Cantwell Olivia M, Pisors Eileen D, Han Lu, MacWilliams Maria P, Jiang Hao, Zhou Fulai, Chiu Mark L

Antibody Structure and Function: The Basis for Engineering Therapeutics

抗体结构与功能：治疗工程的基础

期刊:Antibodies

影响因子:2.7

doi:10.3390/antib8040055

Chiu, Mark L; Goulet, Dennis R; Teplyakov, Alexey; Gilliland, Gary L

发表日期：2019

文献求助收藏

Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody

一种新型变构激动剂/增敏剂胰岛素受体单克隆抗体的独特药理学特性

期刊:Molecular Metabolism

影响因子:6.6

doi:10.1016/j.molmet.2018.01.014

Hinke, Simon A; Cieniewicz, Anne M; Kirchner, Thomas; D'Aquino, Katharine; Nanjunda, Rupesh; Aligo, Jason; Perkinson, Robert; Cooper, Philip; Boayke, Ken; Chiu, Mark L; Jarantow, Steve; Lacy, Eilyn R; Liang, Yin; Johnson, Dana L; Whaley, Jean M; Lingham, Russell B; Kihm, Anthony J

A Dual-Payload Bispecific ADC Improved Potency and Efficacy over Single-Payload Bispecific ADCs.

双有效载荷双特异性抗体药物偶联物 (ADC) 的效力和疗效优于单有效载荷双特异性抗体药物偶联物 (ADC)

A Bispecific Antibody Blocking Both TSLP and IL-4Rα for the Treatment of Allergic Inflammatory Diseases

双特异性抗体阻断TSLP和IL-4Rα治疗过敏性炎症疾病

Targeted Hyaluronan Degradation Enhanced Tumor Growth Inhibition in Gastrointestinal Cancer Models.

靶向透明质酸降解增强了胃肠道癌症模型中的肿瘤生长抑制作用。

Discovery and Phase 1 study of a novel monoclonal antibody against human IL-1β for the treatment of IL-1β-mediated diseases

针对人IL-1β的新型单克隆抗体的发现和I期研究，用于治疗IL-1β介导的疾病

A trispecific antibody targeting EGFR/cMET/VEGF-A demonstrates multiple mechanisms of action to inhibit wild-type and mutant NSCLC animal models.

针对 EGFR/cMET/VEGF-A 的三特异性抗体表现出多种作用机制，可抑制野生型和突变型 NSCLC 动物模型

Guidelines in the Preparation of Fully Synthetic, Human Single-Domain Antibody Phage Display Libraries.

全合成人源单域抗体噬菌体展示文库的制备指南

A novel monoclonal antibody against human thymic stromal lymphopoietin for the treatment of TSLP-mediated diseases

一种新型抗人胸腺基质淋巴细胞生成素单克隆抗体，用于治疗TSLP介导的疾病

The process using a synthetic library that generates multiple diverse human single domain antibodies.

该方法利用合成文库生成多种不同的人类单域抗体

Antibody Structure and Function: The Basis for Engineering Therapeutics

抗体结构与功能：治疗工程的基础

Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody

一种新型变构激动剂/增敏剂胰岛素受体单克隆抗体的独特药理学特性