Collagen-binding IL-12-armoured STEAP1 CAR-T cells reduce toxicity and treat prostate cancer in mouse models
胶原蛋白结合的IL-12修饰的STEAP1 CAR-T细胞可降低毒性并治疗小鼠模型中的前列腺癌
期刊:Nature Biomedical Engineering
影响因子:26.6
doi:10.1038/s41551-025-01508-3
Sasaki, Koichi; Bhatia, Vipul; Asano, Yuta; Bakhtiari, Jakob; Kaur, Pooja; Wang, Chuyi; Matsuo, Takumi; Dubois, Olivier; Chiu, Po-Chuan; Gun, Donny; Singh, Charanjit; Panagi, Ioanna; Noblecourt, Laurine; Nikolaidi, Maria; Chong, Truman; Javier, Gerardo; Priceman, Saul J; Chapuis, Aude G; Lee, John K; Ishihara, Jun
肿瘤
T细胞
肿瘤免疫
毒理研究
T细胞
细胞生物学
前列腺癌
免疫/内分泌
