日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cloning-Free Genome Editing by CRISPR/T7RNAP/Cas9 in Trypanosoma cruzi

利用 CRISPR/T7RNAP/Cas9 技术对克氏锥虫进行无克隆基因组编辑

Chiurillo, Miguel A; Ahmed, Milad; González, César; Rosón, Juliana Nunes; Das, Asima; Lander, Noelia

TcCARP3 modulates compartmentalized cAMP signals involved in osmoregulation, infection of mammalian cells, and colonization of the triatomine vector in the human pathogen Trypanosoma cruzi

TcCARP3 调节参与渗透压调节、哺乳动物细胞感染以及人类病原体克氏锥虫锥蝽媒介定植的区室化 cAMP 信号。

Carlson, Joshua; Ahmed, Milad; Hunter, Riley; Hoque, Syeda Farjana; Benoit, Joshua B; Chiurillo, Miguel A; Lander, Noelia

Generation of inositol polyphosphates through a phospholipase C-independent pathway involving carbohydrate and sphingolipid metabolism in Trypanosoma cruzi.

克氏锥虫通过不依赖于磷脂酶 C 的途径,利用碳水化合物和鞘脂代谢生成肌醇多磷酸盐

Bertolini Mayara S, Cline Sabrina E, Chiurillo Miguel A, Mantilla Brian S, Eidex Aharon, Crowe Logan P, Qiu Danye, Jessen Henning J, Saiardi Adolfo, Docampo Roberto

mSphere of Influence: The challenge of screening for essential protein kinases in Trypanosoma cruzi

mSphere of 影响范围:筛选克氏锥虫必需蛋白激酶的挑战

Chiurillo, Miguel A

Cyclic AMP compartmentalization drives signal specificity to control vector colonization and mammalian host infection by American trypanosomes

环磷酸腺苷(cAMP)区室化驱动信号特异性,从而控制美洲锥虫对媒介的定殖和对哺乳动物宿主的感染。

Ahmed, Milad; Carlson, Joshua; Das, Asima; Hoque, Syeda Farjana; Benoit, Joshua B; Chiurillo, Miguel A; Lander, Noelia

A key regulator of male gametogenesis in Cryptosporidium

隐孢子虫雄性配子发生的关键调控因子

Lander, Noelia; Chiurillo, Miguel A

Dual localization of receptor-type adenylate cyclases and cAMP response protein 3 unveils the presence of two putative signaling microdomains in Trypanosoma cruzi.

受体型腺苷酸环化酶和 cAMP 反应蛋白 3 的双重定位揭示了克氏锥虫中两个假定的信号微区的存在

Chiurillo Miguel A, Carlson Joshua, Bertolini Mayara S, Raja Aqsa, Lander Noelia

High-Accuracy Neuro-Navigation with Computer Vision for Frameless Registration and Real-Time Tracking

基于计算机视觉的高精度神经导航,用于无框架配准和实时跟踪

Chiurillo, Isabella; Sha, Raahil M; Robertson, Faith C; Liu, Jian; Li, Jacqueline; Le Mau, Hieu; Amich, Jose M; Gormley, William B; Stolyarov, Roman

Gene editing of putative cAMP and Ca(2+) -regulated proteins using an efficient cloning-free CRISPR/Cas9 system in Trypanosoma cruzi.

利用高效无克隆 CRISPR/Cas9 系统对克氏锥虫中假定的 cAMP 和 Ca(2+) 调节蛋白进行基因编辑

Chiurillo Miguel A, Ahmed Milad, González César, Raja Aqsa, Lander Noelia

Ablation of the P21 Gene of Trypanosoma cruzi Provides Evidence of P21 as a Mediator in the Control of Epimastigote and Intracellular Amastigote Replication

克氏锥虫 P21 基因的消融提供了 P21 作为控制上鞭毛体和细胞内无鞭毛体复制的介质的证据

Thaise Lara Teixeira, Miguel Angel Chiurillo, Noelia Lander, Cassiano Costa Rodrigues, Thiago Souza Onofre, Éden Ramalho Ferreira, Camila Miyagui Yonamine, Júlia de Gouveia Santos, Renato Arruda Mortara, Claudio Vieira da Silva, José Franco da Silveira