日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Prevalence of cytopenia(s) and somatic variants in patients with DDX41 mutant germline predisposition syndrome

DDX41突变种系易感综合征患者中细胞减少症和体细胞变异的患病率

Kusne, Yael; Badar, Talha; Lasho, Terra; Marando, Ludovica; Mangaonkar, Abhishek A; Finke, Christy; Foran, James M; Al-Kali, Aref; Palmer, Jeanne; Arana Yi, Cecilia; Alkhateeb, Hassan B; Gangat, Naseema; Viswanatha, David; Litzow, Mark R; Chlon, Timothy; Ferrer, Alejandro; Patnaik, Mrinal M

Germline DDX41 mutations in myeloid neoplasms: the current clinical and molecular understanding

髓系肿瘤中的种系DDX41突变:目前的临床和分子认识

Kida, Junichiro; Chlon, Timothy M

DDX41 haploinsufficiency causes inefficient hematopoiesis under stress and cooperates with p53 mutations to cause hematologic malignancy

DDX41 单倍体不足导致应激状态下造血效率低下,并与 p53 突变协同导致血液系统恶性肿瘤

Emily Stepanchick, Andrew Wilson, Analise M Sulentic, Kwangmin Choi, Kathleen Hueneman, Daniel T Starczynowski, Timothy M Chlon

Clinical and molecular correlates of somatic and germline DDX41 variants in patients and families with myeloid neoplasms

髓系肿瘤患者及其家族中体细胞和生殖细胞DDX41变异的临床和分子相关性

Badar, Talha; Nanaa, Ahmad; Foran, James M; Viswanatha, David; Al-Kali, Aref; Lasho, Terra; Finke, Christy; Alkhateeb, Hassan B; He, Rong; Gangat, Naseema; Shah, Mithun; Tefferi, Ayalew; Mangaonkar, Abhishek A; Litzow, Mark R; Ongie, Laura J; Chlon, Timothy; Ferrer, Alejandro; Patnaik, Mrinal M

The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia

去泛素化酶 USP15 调节细胞氧化还原,是急性髓系白血病的治疗靶点

Madeline Niederkorn, Chiharu Ishikawa, Kathleen M Hueneman, James Bartram, Emily Stepanchick, Joshua R Bennett, Ashley E Culver-Cochran, Lyndsey C Bolanos, Emma Uible, Kwangmin Choi, Mark Wunderlich, John P Perentesis, Timothy M Chlon, Marie-Dominique Filippi, Daniel T Starczynowski

Germline and Somatic Defects in DDX41 and its Impact on Myeloid Neoplasms

DDX41基因的种系和体细胞缺陷及其对髓系肿瘤的影响

Badar, Talha; Chlon, Timothy

Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin

遗传性 DNA 修复缺陷破坏人类皮肤的结构和功能

Sonya Ruiz-Torres, Marion G Brusadelli, David P Witte, Kathryn A Wikenheiser-Brokamp, Sharon Sauter, Adam S Nelson, Mathieu Sertorio, Timothy M Chlon, Adam Lane, Parinda A Mehta, Kasiani C Myers, Mary C Bedard, Bidisha Pal, Dorothy M Supp, Paul F Lambert, Kakajan Komurov, Melinda Butsch Kovacic, Ste

Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia

种系 DDX41 突变导致造血无效和骨髓发育不良

Timothy M Chlon, Emily Stepanchick, Courtney E Hershberger, Noah J Daniels, Kathleen M Hueneman, Ashley Kuenzi Davis, Kwangmin Choi, Yi Zheng, Carmelo Gurnari, Torsten Haferlach, Richard A Padgett, Jaroslaw P Maciejewski, Daniel T Starczynowski

Chronic immune response dysregulation in MDS pathogenesis

MDS发病机制中的慢性免疫反应失调

Barreyro, Laura; Chlon, Timothy M; Starczynowski, Daniel T

Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study

乳腺癌免疫浸润模式及其临床意义:一项基于基因表达的回顾性研究

Ali, H Raza; Chlon, Leon; Pharoah, Paul D P; Markowetz, Florian; Caldas, Carlos