Cho Kwang-Jin相关文献与解析，生知库 | 链接生命科学的每一步

Sd-021, derivatives of decursin, inhibits tumorigenesis in NSCLC by inhibiting the EGFR/STAT3 signaling pathway.

Sd-021 是 decursin 的衍生物，它通过抑制 EGFR/STAT3 信号通路来抑制 NSCLC 的肿瘤发生

Hwang Hyun-Ha, Je Jeong-Hui, Lee Hyeong-Chan, Yoo Ji-Sung, Kim Taehyoun, Choi Jung Hwan, Hong Jin Won, Lim Hae-In, Kim Ga Yoon, Sim Yun-Beom, Cho Kwang-Jin, Choi Eun-Wook, Cheon Chunhoo, Lee Jae Yeol, Ko Seong-Gyu

信号转导

A new ferrocene derivative blocks KRAS localization and function by oxidative modification at His95

一种新型二茂铁衍生物通过对 His95 位点的氧化修饰阻断 KRAS 的定位和功能。

期刊:

影响因子:

doi:10.1101/2023.03.28.534499

Rehl, Kristen M; Selvakumar, Jayaraman; Hoang, Don; Arumugam, Kuppuswamy; Gorfe, Alemayehu A; Cho, Kwang-Jin

RAS

发表日期：2023

文献求助收藏

Scaffold repurposing of fendiline: Identification of potent KRAS plasma membrane localization inhibitors

芬地林支架的重新利用：鉴定强效的KRAS质膜定位抑制剂

期刊:European Journal of Medicinal Chemistry

影响因子:5.9

doi:10.1016/j.ejmech.2021.113381

Wang, Pingyuan; van der Hoeven, Dharini; Ye, Na; Chen, Haiying; Liu, Zhiqing; Ma, Xiaoping; Montufar-Solis, Dina; Rehl, Kristen M; Cho, Kwang-Jin; Thapa, Sabita; Chen, Wei; van der Hoeven, Ransome; Frost, Jeffrey A; Hancock, John F; Zhou, Jia

RAS

发表日期：2021

文献求助收藏

Blocking K-Ras Interaction With the Plasma Membrane Is a Tractable Therapeutic Approach to Inhibit Oncogenic K-Ras Activity

阻断K-Ras与质膜的相互作用是抑制致癌K-Ras活性的可行治疗方法。

期刊:Frontiers in Molecular Biosciences

影响因子:4

doi:10.3389/fmolb.2021.673096

Henkels, Karen M; Rehl, Kristen M; Cho, Kwang-Jin

Editorial: Ras and Other GTPases in Cancer: From Basic to Applied Research

社论：Ras 和其他 GTP 酶在癌症中的作用：从基础研究到应用研究

期刊:Frontiers in Molecular Biosciences

影响因子:4

doi:10.3389/fmolb.2021.804818

Cho, Kwang-Jin; Liang, Jin Rui; Crespo, Piero; Aran, Veronica

Lipidomic atlas of mammalian cell membranes reveals hierarchical variation induced by culture conditions, subcellular membranes, and cell lineages

哺乳动物细胞膜脂质组学图谱揭示了培养条件、亚细胞膜和细胞谱系引起的层级变异

期刊:Soft Matter

影响因子:2.8

doi:10.1039/d0sm00404a

Symons, Jessica L; Cho, Kwang-Jin; Chang, Jeffrey T; Du, Guangwei; Waxham, M Neal; Hancock, John F; Levental, Ilya; Levental, Kandice R

细胞生物学

发表日期：2021

文献求助收藏

Chalcones bearing a 3,4,5-trimethoxyphenyl motif are capable of selectively inhibiting oncogenic K-Ras signaling

含有3,4,5-三甲氧基苯基结构的查尔酮能够选择性地抑制致癌的K-Ras信号通路。

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2020.127144

Kovar, Sarah E; Fourman, Cody; Kinstedt, Christine; Williams, Brandon; Morris, Christopher; Cho, Kwang-Jin; Ketcha, Daniel M

SIGNAL TRANSDUCTION. Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling

信号转导。膜电位调节质膜磷脂动力学和K-Ras信号传导。

期刊:Science

影响因子:45.8

doi:10.1126/science.aaa5619

Zhou, Yong; Wong, Ching-On; Cho, Kwang-jin; van der Hoeven, Dharini; Liang, Hong; Thakur, Dhananiay P; Luo, Jialie; Babic, Milos; Zinsmaier, Konrad E; Zhu, Michael X; Hu, Hongzhen; Venkatachalam, Kartik; Hancock, John F

信号转导

发表日期：2015

文献求助收藏

Rare Streptomyces N-formyl amino-salicylamides inhibit oncogenic K-Ras

罕见的链霉菌N-甲酰氨基水杨酰胺抑制致癌K-Ras

期刊:Organic Letters

影响因子:5

doi:10.1021/ol502376e

Salim, Angela A; Cho, Kwang-Jin; Tan, Lingxiao; Quezada, Michelle; Lacey, Ernest; Hancock, John F; Capon, Robert J

MTMR regulates KRAS function by controlling plasma membrane levels of phospholipids.

MTMR通过控制质膜磷脂水平来调节KRAS功能

Sd-021, derivatives of decursin, inhibits tumorigenesis in NSCLC by inhibiting the EGFR/STAT3 signaling pathway.

Sd-021 是 decursin 的衍生物，它通过抑制 EGFR/STAT3 信号通路来抑制 NSCLC 的肿瘤发生

A new ferrocene derivative blocks KRAS localization and function by oxidative modification at His95

一种新型二茂铁衍生物通过对 His95 位点的氧化修饰阻断 KRAS 的定位和功能。

Scaffold repurposing of fendiline: Identification of potent KRAS plasma membrane localization inhibitors

芬地林支架的重新利用：鉴定强效的KRAS质膜定位抑制剂

Blocking K-Ras Interaction With the Plasma Membrane Is a Tractable Therapeutic Approach to Inhibit Oncogenic K-Ras Activity

阻断K-Ras与质膜的相互作用是抑制致癌K-Ras活性的可行治疗方法。

Editorial: Ras and Other GTPases in Cancer: From Basic to Applied Research

社论：Ras 和其他 GTP 酶在癌症中的作用：从基础研究到应用研究

Lipidomic atlas of mammalian cell membranes reveals hierarchical variation induced by culture conditions, subcellular membranes, and cell lineages

哺乳动物细胞膜脂质组学图谱揭示了培养条件、亚细胞膜和细胞谱系引起的层级变异

Chalcones bearing a 3,4,5-trimethoxyphenyl motif are capable of selectively inhibiting oncogenic K-Ras signaling

含有3,4,5-三甲氧基苯基结构的查尔酮能够选择性地抑制致癌的K-Ras信号通路。

SIGNAL TRANSDUCTION. Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling

信号转导。膜电位调节质膜磷脂动力学和K-Ras信号传导。

Rare Streptomyces N-formyl amino-salicylamides inhibit oncogenic K-Ras

罕见的链霉菌N-甲酰氨基水杨酰胺抑制致癌K-Ras