Choon Kiat相关文献与解析，生知库 | 链接生命科学的每一步

Chan, Jason Yongsheng; Lee, Elizabeth Chun Yong; Chai, Kelila Xin Ye; Lim, Boon Yee; Li, Zhimei; Lee, Jing Yi; Kannan, Bavani; Tay, Hui Yi; Ko, Tun Kiat; Kok, Jessica Sook-Ting; Lim, Kah Suan; Taib, Nur Ayuni Binte Muhammad; Huang, Dachuan; Lim, Jing Quan; Hazama, Masatoshi; Fukushima, Koji; Teh, Bin Tean; Lim, Soon Thye; Ong, Choon Kiat

细胞生物学

淋巴瘤

T细胞

发表日期：2026

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Epstein-Barr virus hijacks histone demethylase machinery to drive epithelial malignancy progression through KDM5B upregulation

EB 病毒劫持组蛋白去甲基化酶机制，通过 KDM5B 上调推动上皮恶性肿瘤进展

期刊:Signal Transduction and Targeted Therapy

影响因子:40.8

doi:10.1038/s41392-025-02163-5

Ya-Qing Zhou, Jia-Xin Jiang, Shuai He, Yi-Qi Li, Xi-Xi Cheng, Shu-Qiang Liu, Pan-Pan Wei, Xin-Yuan Guan, Choon Kiat Ong, Vivien Ya-Fan Wang, Chun-Ling Luo, Jin-Xin Bei4

Priming with DNMT Inhibitors Potentiates PD-1 Immunotherapy by Triggering Viral Mimicry in Relapsed/Refractory NK/T-cell Lymphoma

DNMT抑制剂预处理可通过触发病毒模拟增强PD-1免疫疗法在复发/难治性NK/T细胞淋巴瘤中的疗效

期刊:

影响因子:29.7

doi:PMC12670078

Cheng Huang #，Yan Gao #，Jianfeng Chen #，Jing Han Hong，Yue Jiang，Kelila Xin Ye Chai，Yingxi Li，Peili Wang，Yali Wang，Jiuping Gao，Xian Zeng，Rong Xiao，Haixia He，Peiyong Guan，Jason Yongsheng Chan，Jing Quan Lim，Anand D Jeyasekharan ，Huang Dachuan，Jin-Xin Bei，Bin Tean Teh ，Soon Thye Lim，Qiang Yu，Choon Kiat Ong ，Huiqiang Huang，Jing Tan

Priming with DNMT Inhibitors Potentiates PD-1 Immunotherapy by Triggering Viral Mimicry in Relapsed/Refractory NK/T-cell Lymphoma

DNMT抑制剂预处理可通过触发病毒模拟增强PD-1免疫疗法在复发/难治性NK/T细胞淋巴瘤中的疗效

期刊:Cancer Discovery

影响因子:29.7

doi:10.1158/2159-8290.CD-25-0587

Cheng Huang # ，Yan Gao # ，Jianfeng Chen # ，Jing Han Hong ，Yue Jiang ，Kelila Xin Ye Chai ，Yingxi Li ，Peili Wang ，Yali Wang ，Jiuping Gao ，Xian Zeng ，Rong Xiao ，Haixia He ，Peiyong Guan ，Jason Yongsheng Chan ，Jing Quan Lim ，Anand D Jeyasekharan ，Huang Dachuan ，Jin-Xin Bei ，Bin Tean Teh ，Soon Thye Lim ，Qiang Yu ，Choon Kiat Ong ，Huiqiang Huang ，Jing Tan

PARP inhibitor augments anti-tumor efficacy of DNMT inhibitor by inducing senescence in cholangiocarcinoma.

PARP抑制剂通过诱导胆管癌细胞衰老来增强DNMT抑制剂的抗肿瘤功效

期刊:International Journal of Biological Sciences

影响因子:10

doi:10.7150/ijbs.110947

Wang Peili, Xiao Rong, Chen Jianfeng, Guan Peiyong, Heng Hong Lee, Liu Lizhen, Wang Yali, Zeng Xian, Zhong Guixiang, Hao Jing, Gao Jiuping, Chan Jason Yongsheng, Dima Simona, Ong Choon Kiat, Teh Bin Tean, Li Mei, Hong Jing Han, Tan Jing

Characterizing Nodal Gamma-Delta T-Cell Lymphoma: Clinicopathological and Molecular Insights

淋巴结γδT细胞淋巴瘤的特征：临床病理学和分子生物学见解

期刊:Modern Pathology

影响因子:5.5

doi:10.1016/j.modpat.2024.100685

Oon, Ming Liang; Lim, Jing Quan; Bosch-Schips, Jan; Climent, Fina; Au-Yeung, Rex K H; Hutchison, Bailey; Sohani, Aliyah R; Eren, Ozgur Can; Kumar, Jyoti; Dogan, Ahmet; Ong, Choon-Kiat; Quintanilla-Martinez, Leticia; Ng, Siok-Bian

Establishment and characterization of a novel patient-derived TP63-rearranged anaplastic large-cell lymphoma model PTCL-S1

建立和表征一种新型患者来源的TP63重排间变性大细胞淋巴瘤模型PTCL-S1

期刊:Human Cell

影响因子:3.1

doi:10.1007/s13577-025-01264-1

Chai, Kelila Xin Ye; Lee, Elizabeth Chun Yong; Li, Zhimei; Muhammad, Nur Ayuni Binte; Lim, Jing Quan; Huang, Dachuan; Lim, Soon Thye; Chan, Jason Yongsheng; Ong, Choon Kiat

Outcomes of primary CNS lymphoma treated with combined immunochemotherapy with whole-brain radiotherapy

采用免疫化疗联合全脑放疗治疗原发性中枢神经系统淋巴瘤的疗效

期刊:Annals of Hematology

影响因子:2.4

doi:10.1007/s00277-025-06561-1

Tan, Ya Hwee; Lim, Ryan Mao Heng; Tan, Jing Yuan; Lim, Boon Yee; Binte, Nur Ayuni; Taib, Muhammad; Ong, Choon Kiat; Cheng, Chee Leong; Yeoh, Kheng Wei; Lim, Soon Thye; Chan, Jason Yongsheng

Next-Generation Integrated Sequencing Identifies Poor Prognostic Factors in Patients with MYD88-Mutated Chronic Lymphocytic Leukemia in Taiwan

台湾新一代整合测序技术揭示MYD88突变型慢性淋巴细胞白血病患者预后不良因素

期刊:Pathobiology

影响因子:2

doi:10.1159/000541709

Huang, Ying-Jung; Lim, Jing Quan; Hsu, Jacob Shujui; Kuo, Ming-Chung; Wang, Po-Nan; Kao, Hsiao-Wen; Wu, Jin-Hou; Chen, Chiu-Chen; Tsai, Shih-Feng; Ong, Choon Kiat; Shih, Lee-Yung

Indolent nodal T follicular helper cell lymphomas-A case series

惰性淋巴结T滤泡辅助细胞淋巴瘤——病例系列

期刊:Blood Cancer Journal

影响因子:11.6

doi:10.1038/s41408-024-01163-y

Wang, Jie; Yau, Chun En; Low, Chen Ee; Bin Hasan Mohamed, Mohamed Haniffa; Cheng, Chee Leong; Neff, Jadee L; Lim, Jing Quan; Lim, Soon Thye; Chan, Jason Yongsheng; Ong, Choon Kiat; Yang, Valerie Shiwen

Preclinical activity of brincidofovir in peripheral T-cell and NK/T-cell lymphoma

brincidofovir 在外周 T 细胞和 NK/T 细胞淋巴瘤中的临床前活性

Epstein-Barr virus hijacks histone demethylase machinery to drive epithelial malignancy progression through KDM5B upregulation

EB 病毒劫持组蛋白去甲基化酶机制，通过 KDM5B 上调推动上皮恶性肿瘤进展

Priming with DNMT Inhibitors Potentiates PD-1 Immunotherapy by Triggering Viral Mimicry in Relapsed/Refractory NK/T-cell Lymphoma

DNMT抑制剂预处理可通过触发病毒模拟增强PD-1免疫疗法在复发/难治性NK/T细胞淋巴瘤中的疗效

Priming with DNMT Inhibitors Potentiates PD-1 Immunotherapy by Triggering Viral Mimicry in Relapsed/Refractory NK/T-cell Lymphoma

DNMT抑制剂预处理可通过触发病毒模拟增强PD-1免疫疗法在复发/难治性NK/T细胞淋巴瘤中的疗效

PARP inhibitor augments anti-tumor efficacy of DNMT inhibitor by inducing senescence in cholangiocarcinoma.

PARP抑制剂通过诱导胆管癌细胞衰老来增强DNMT抑制剂的抗肿瘤功效

Characterizing Nodal Gamma-Delta T-Cell Lymphoma: Clinicopathological and Molecular Insights

淋巴结γδT细胞淋巴瘤的特征：临床病理学和分子生物学见解

Establishment and characterization of a novel patient-derived TP63-rearranged anaplastic large-cell lymphoma model PTCL-S1

建立和表征一种新型患者来源的TP63重排间变性大细胞淋巴瘤模型PTCL-S1

Outcomes of primary CNS lymphoma treated with combined immunochemotherapy with whole-brain radiotherapy

采用免疫化疗联合全脑放疗治疗原发性中枢神经系统淋巴瘤的疗效

Next-Generation Integrated Sequencing Identifies Poor Prognostic Factors in Patients with MYD88-Mutated Chronic Lymphocytic Leukemia in Taiwan

台湾新一代整合测序技术揭示MYD88突变型慢性淋巴细胞白血病患者预后不良因素

Indolent nodal T follicular helper cell lymphomas-A case series

惰性淋巴结T滤泡辅助细胞淋巴瘤——病例系列