Choonghee相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Explainable Machine Learning for Assessing Digital Health Literacy in Older Adults: Validation and Development of a Two-Stage Model Integrating Performance-Based and Self-Assessed Indicators

利用可解释机器学习评估老年人的数字健康素养：验证和开发整合基于表现和自我评估指标的两阶段模型

期刊:JMIR Medical Informatics

影响因子:3.8

doi:10.2196/86171

Park, Choonghee; Park, Jiyeon; Kim, Seora; Bae, Ye Seul; Kang, Jae-Heon; Kim, Tae-Min; Chun, Ji-Won

发表日期：2026

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Lemborexant ameliorates tau-mediated sleep loss and neurodegeneration in males in a mouse model of tauopathy.

在 tau 蛋白病小鼠模型中，Lemborexant 可改善 tau 蛋白介导的雄性睡眠丧失和神经退行性变

期刊:Nature Neuroscience

影响因子:20

doi:10.1038/s41593-025-01966-7

Parhizkar Samira, Bao Xin, Chen Wei, Rensing Nicholas, Chen Yun, Kipnis Michal, Song Sihui, Gent Grace, Tycksen Eric, Manis Melissa, Lee Choonghee, Serrano Javier Remolina, Bosch Megan E, Franke Emily, Yuede Carla M, Landsness Eric C, Wong Michael, Holtzman David M

发表日期：2025

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Measuring Digital Health Literacy in Older Adults: Development and Validation Study

老年人数字健康素养测量：开发与验证研究

期刊:Journal of Medical Internet Research

doi:10.2196/65492

Kim, SungMin; Park, Choonghee; Park, Sunghyeon; Kim, Dai-Jin; Bae, Ye-Seul; Kang, Jae-Heon; Chun, Ji-Won

发表日期：2025

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Correction: Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner

更正：寡甘露酸钠以性别特异性方式改变肠道菌群，减少脑淀粉样变性和反应性小胶质细胞。

期刊:Molecular Neurodegeneration

影响因子:17.5

doi:10.1186/s13024-024-00764-2

Bosch, Megan E; Dodiya, Hemraj B; Michalkiewicz, Julia; Lee, Choonghee; Shaik, Shabana M; Weigle, Ian Q; Zhang, Can; Osborn, Jack; Nambiar, Aishwarya; Patel, Priyam; Parhizkar, Samira; Zhang, Xiaoqiong; Laury, Marie L; Mondal, Prasenjit; Gomm, Ashley; Schipma, Matthew John; Mallah, Dania; Butovsky, Oleg; Chang, Eugene B; Tanzi, Rudolph E; Gilbert, Jack A; Holtzman, David M; Sisodia, Sangram S

细胞生物学

发表日期：2024

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Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner

甘露寡酸钠以性别特异性的方式改变肠道菌群、减少脑淀粉样变性和反应性小胶质细胞

期刊:Molecular Neurodegeneration

影响因子:14.9

doi:10.1186/s13024-023-00700-w

Megan E Bosch #, Hemraj B Dodiya #, Julia Michalkiewicz #, Choonghee Lee #, Shabana M Shaik #, Ian Q Weigle, Can Zhang, Jack Osborn, Aishwarya Nambiar, Priyam Patel, Samira Parhizkar, Xiaoqiong Zhang, Marie L Laury, Prasenjit Mondal, Ashley Gomm, Matthew John Schipma, Dania Mallah, Oleg Butovsky, Eu

细胞生物学

发表日期：2024

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Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

LXR激动剂可改善Tau蛋白和ApoE4相关的胶质细胞脂质积累和神经退行性变

影响因子:14.7

doi:10.1016/j.neuron.2023.10.023

Alexandra Litvinchuk ，Jung H Suh ，Jing L Guo ，Karin Lin ，Sonnet S Davis ，Nga Bien-Ly ，Eric Tycksen ，G Travis Tabor ，Javier Remolina Serrano ，Melissa Manis ，Xin Bao ，Choonghee Lee ，Megan Bosch ，Enmanuel J Perez ，Carla M Yuede ，Anil G Cashikar ，Jason D Ulrich ，Gilbert Di Paolo ，David M Holtzman

细胞生物学

发表日期：2024

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Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2-dependent manner in mice

睡眠不足以 TREM2 依赖的方式加剧小鼠的小胶质细胞反应性和 Aβ 沉积

期刊:Science Translational Medicine

影响因子:15.8

doi:10.1126/scitranslmed.ade6285

Samira Parhizkar, Grace Gent, Yun Chen, Nicholas Rensing, Maud Gratuze, Gregory Strout, Sanja Sviben, Eric Tycksen, Qiang Zhang, Petra Erdmann Gilmore, Robert Sprung, Jim Malone, Wei Chen, Javier Remolina Serrano, Xin Bao, Choonghee Lee, Chanung Wang, Eric Landsness, James Fitzpatrick, Michael Wong,

细胞生物学

发表日期：2023

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Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy

尽管脑淀粉样血管病增多，但去除星形胶质细胞 APOE4 仍能提供脑血管保护

期刊:Molecular Neurodegeneration

影响因子:14.9

doi:10.1186/s13024-023-00610-x

Monica Xiong #, Chao Wang #, Maud Gratuze #, Fareeha Saadi, Xin Bao, Megan E Bosch, Choonghee Lee, Hong Jiang, Javier Remolina Serrano, Ernesto R Gonzales, Michal Kipnis, David M Holtzman

细胞生物学

发表日期：2023

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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4

在 ApoE4 存在的情况下，TREM2 非依赖性小胶质细胞增生促进 tau 介导的神经退行性变

影响因子:14.7

doi:10.1016/j.neuron.2022.10.022

Maud Gratuze ，Johannes C M Schlachetzki ，Ricardo D'Oliveira Albanus ，Nimansha Jain ，Brenna Novotny ，Logan Brase ，Lea Rodriguez ，Clayton Mansel ，Michal Kipnis ，Sydney O'Brien ，Martina P Pasillas ，Choonghee Lee ，Melissa Manis ，Marco Colonna ，Oscar Harari ，Christopher K Glass ，Jason D Ulrich ，David M Holtzman

细胞生物学

发表日期：2023

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APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading

APOE-ε4 与睡眠中断协同作用，加速 Aβ 沉积以及 Aβ 相关的 tau 的播种和扩散

期刊:Journal of Clinical Investigation

影响因子:13.3

doi:10.1172/JCI169131

Chanung Wang, Aishwarya Nambiar, Michael R Strickland, Choonghee Lee, Samira Parhizkar, Alec C Moore, Erik S Musiek, Jason D Ulrich, David M Holtzman

发表日期：2023

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