TYRA-300, an FGFR3-selective inhibitor, promotes bone growth in two FGFR3-driven models of chondrodysplasia
TYRA-300 是一种 FGFR3 选择性抑制剂,可在两种 FGFR3 驱动的软骨发育不良模型中促进骨骼生长。
期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.189307
Starrett, Jacqueline H; Lemoine, Clara; Guillo, Matthias; Fayad, Chantal; Kaci, Nabil; Neal, Melissa; Pettitt, Emily A; Pache, Melissandre; Ye, Qing; Chouinard, My; Allen, Eric L; Baujat, Geneviève; Hudkins, Robert L; Bober, Michael B; Harris, Todd; Swanson, Ronald V; Legeai-Mallet, Laurence