日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Accumulated mtDNA mutations are linked to specific impairments in NADH-linked respiration

线粒体DNA突变的积累与NADH依赖性呼吸作用的特定缺陷有关

Franczak, Edziu; Montgomery, McLane M; Terwilliger, Zoe S; Aruleba, Raphael T; Krassovskaia, Polina; Boykov, Ilya N; Hagen, James T; Pacheco, Emely A; Chrest, Brett R; Zeczycki, Tonya N; Vandiver, Kayla J; Neufer, P Darrell; McClung, Joseph M; Fisher-Wellman, Kelsey H

Acute myeloid leukemia mitochondria hydrolyze ATP to support oxidative metabolism and resist chemotherapy

急性髓系白血病线粒体水解ATP以支持氧化代谢并抵抗化疗

James T Hagen,McLane M Montgomery,Raphael T Aruleba,Brett R Chrest,Polina Krassovskaia,Thomas D Green,Emely A Pacheco,Miki Kassai,Tonya N Zeczycki,Cameron A Schmidt,Debajit Bhowmick,Su-Fern Tan,David J Feith,Charles E Chalfant,Thomas P Loughran Jr,Darla Liles,Mark D Minden,Aaron D Schimmer,Md Salman Shakil,Matthew J McBride,Myles C Cabot,Joseph M McClung,Kelsey H Fisher-Wellman

Impact of physiological media on acute myeloid leukemia bioenergetics and cell proliferation.

生理介质对急性髓系白血病生物能量学和细胞增殖的影响

Chrest Brett R, Montgomery McLane M, Aruleba Raphael T, Krassovskaia Polina, Pacheco Emely A, Hagen James T, Vandiver Kayla J, Tung Kang, Alexander Molly K, Williamson Nicholas C, Taylor Joshua G, Bessetti Riley N, Belcher Heather A, Jevtovic Filip, Terwilliger Zoe S, Minchew Everett C, Zeczycki Tonya N, May Linda, Broskey Nicholas T, Geyer Christopher B, Litwa Karen, Spangenburg Espen E, Hannan Johanna L, Ellis Jessica M, McClung Joseph M, Neufer P Darrell, Fisher-Wellman Kelsey H

Chemical-induced colitis lowers mitochondrial bioenergetic function in the colonic epithelium with minimal impacts on the proteome

化学诱导的结肠炎会降低结肠上皮细胞线粒体的生物能量功能,而对蛋白质组的影响甚微。

Montgomery, McLane M; Al Obaidi, Masara A; Aruleba, Raphael T; Krassovskaia, Polina; Pacheco, Emely A; Franczak, Edziu; Chrest, Brett R; Green, Thomas D; Zeczycki, Tonya N; McClung, Joeseph M; Fisher-Wellman, Kelsey H

The MEK inhibitor trametinib incurs mitochondrial injury and induces innate immune responses in the mouse heart

MEK抑制剂曲美替尼可导致小鼠心脏线粒体损伤并诱导先天免疫反应

Fisher-Wellman, Kelsey H; Lutze, Richard D; Kirkland, Logan G; Beak, Ju Youn; Morrissey, Samantha M; Sandroni, Peyton B; Huang, Wei; Bailon, Julian D; Schroder, Melissa A; Albrecht, Lars A; Goyal, Mansi; Chin, Andrew L; Green, Thomas D; McClung, Joseph M; Montgomery, McLane M; Hagen, James T; Chrest, Brett R; Zawistowski, Jon S; Stuhlmiller, Timothy J; Gomez, Shawn M; Prathumsap, Nanthip; Zhang, Qing; Zhang, Jing; Xu, Weiyi; Zhang, Lilei; Meier, Jeremy A; Carey, Lisa A; Schisler, Jonathan C; Johnson, Gary L; Jensen, Brian C

Mitochondria inside acute myeloid leukemia cells hydrolyze ATP to resist chemotherapy

急性髓系白血病细胞内的线粒体水解ATP以抵抗化疗

James T Hagen, Mclane M Montgomery, Raphael T Aruleba, Brett R Chrest, Thomas D Green, Miki Kassai, Tonya N Zeczycki, Cameron A Schmidt, Debajit Bhowmick, Su-Fern Tan, David J Feith, Charles E Chalfant, Thomas P Loughran Jr, Darla Liles, Mark D Minden, Aaron D Schimmer, Myles C Cabot, Joseph M Mclun

Requirement of the expression of 3-phosphoglycerate dehydrogenase for traversing S phase in murine T lymphocytes following immobilized anti-CD3 activation

小鼠T淋巴细胞在固定化抗CD3激活后,需要表达3-磷酸甘油酸脱氢酶才能进入S期

Jun, Do Youn; Taub, Dennis; Chrest, Francis J; Kim, Young Ho

Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42)

纤维状 Aβ(1-42) 刺激内皮细胞产生更多 Aβ(1-40)

Jayakumar Rajadas, Wenchao Sun, Hai Li, Mohammed Inayathullah, Damiano Cereghetti, Aaron Tan, Valeria de Mello Coelho, Francis J Chrest, John W Kusiak, Wanli Wei Smith, Dennis Taub, Joseph C Wu, Joseph M Rifkind

Late stage erythroid precursor production is impaired in mice with chronic inflammation

慢性炎症小鼠的晚期红系前体细胞生成受损。

Prince, Olivier D; Langdon, Jacqueline M; Layman, Andrew J; Prince, Ian C; Sabogal, Miguel; Mak, Howard H; Berger, Alan E; Cheadle, Chris; Chrest, Francis J; Yu, Qilu; Andrews, Nancy C; Xue, Qian-Li; Civin, Curt I; Walston, Jeremy D; Roy, Cindy N

Quantifying interhospital patient sharing as a mechanism for infectious disease spread

量化医院间患者共享作为传染病传播机制

Huang, Susan S; Avery, Taliser R; Song, Yeohan; Elkins, Kristen R; Nguyen, Christopher C; Nutter, Sandra K; Nafday, Alaka A; Condon, Curtis J; Chang, Michael T; Chrest, David; Boos, John; Bobashev, Georgiy; Wheaton, William; Frank, Steven A; Platt, Richard; Lipsitch, Marc; Bush, Robin M; Eubank, Stephen; Burke, Donald S; Lee, Bruce Y