日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Patient-specific computational models predict prognosis in B cell lymphoma by quantifying pro-proliferative and anti-apoptotic signatures from genetic sequencing data

患者特异性计算模型通过量化基因测序数据中的促增殖和抗凋亡特征来预测B细胞淋巴瘤的预后。

Norris, Richard; Jones, John; Mancini, Erika; Chevassut, Timothy; Simoes, Fabio A; Pepper, Chris; Pepper, Andrea; Mitchell, Simon

Computational modeling of DLBCL predicts response to BH3-mimetics

DLBCL 的计算模型预测对 BH3 类似物的反应

Ielyaas Cloete, Victoria M Smith, Ross A Jackson, Andrea Pepper, Chris Pepper, Meike Vogler, Martin J S Dyer, Simon Mitchell

NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma

NF-κB 指纹揭示弥漫大 B 细胞淋巴瘤中的异质性 NF-κB 组成

Eleanor Jayawant, Arran Pack, Heather Clark, Emma Kennedy, Ankur Ghodke, John Jones, Chris Pepper, Andrea Pepper, Simon Mitchell

Synthesis and Characterization of NUC-7738, an Aryloxy Phosphoramidate of 3'-Deoxyadenosine, as a Potential Anticancer Agent

NUC-7738(3'-脱氧腺苷的芳氧基磷酰胺)的合成与表征,作为潜在的抗癌剂

Michaela Serpi, Valentina Ferrari, Christopher McGuigan, Essam Ghazaly, Chris Pepper

DNA sequence-selective G-A cross-linking ADC payloads for use in solid tumour therapies

DNA 序列选择性 GA 交联 ADC 有效载荷用于实体肿瘤治疗

George Procopiou, Paul J M Jackson, Daniella di Mascio, Jennifer L Auer, Chris Pepper, Khondaker Miraz Rahman, Keith R Fox, David E Thurston

Targeting the Non-Canonical NF-κB Pathway in Chronic Lymphocytic Leukemia and Multiple Myeloma

针对慢性淋巴细胞白血病和多发性骨髓瘤中的非经典 NF-κB 通路

Thomas A Burley, Emma Kennedy, Georgia Broad, Melanie Boyd, David Li, Timothy Woo, Christopher West, Eleni E Ladikou, Iona Ashworth, Christopher Fegan, Rosalynd Johnston, Simon Mitchell, Simon P Mackay, Andrea G S Pepper, Chris Pepper

Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

阐明粘着斑激酶作为迁移和侵袭的调节剂以及作为慢性淋巴细胞白血病的潜在治疗靶点

Thomas A Burley, Andrew Hesketh, Giselda Bucca, Emma Kennedy, Eleni E Ladikou, Benjamin P Towler, Simon Mitchell, Colin P Smith, Christopher Fegan, Rosalynd Johnston, Andrea Pepper, Chris Pepper

Increased frequency of CD4+ PD-1+ HLA-DR+ T cells is associated with disease progression in CLL

CD4+ PD-1+ HLA-DR+ T 细胞频率增加与 CLL 疾病进展相关

Lauren Elston, Chris Fegan, Robert Hills, Shaikh S Hashimdeen, Elisabeth Walsby, Peter Henley, Chris Pepper, Stephen Man

Targeting CDK9 for treatment of colorectal cancer

靶向 CDK9 治疗结直肠癌

Muhammed H Rahaman, Frankie Lam, Longjin Zhong, Theodosia Teo, Julian Adams, Mingfeng Yu, Robert W Milne, Chris Pepper, Noor A Lokman, Carmela Ricciardelli, Martin K Oehler, Shudong Wang

PARP inhibition prevents escape from a telomere-driven crisis and inhibits cell immortalisation

PARP 抑制可防止端粒驱动的危机逃脱并抑制细胞永生化

Greg Ngo, Sam Hyatt, Julia Grimstead, Rhiannon Jones, Eric Hendrickson, Chris Pepper, Duncan Baird