日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immune cell uptake of glycinated nanoparticles conjugated to anti-fibrotic peptides enables their prolonged activity and oral administration

免疫细胞摄取与抗纤维化肽偶联的甘氨酸化纳米颗粒,使其能够延长活性并进行口服给药。

Deidree V N Somanader-Livera ,Chen Wei ,Chao Wang ,Yifang Li ,Dorota Ferens ,Ekaterina Salimova ,Cordelia Selomulya ,Mohammed Akhter Hossain ,Chrishan S Samuel ,Amlan Chakraborty

The novel AT2 receptor ligand, β-Pro7 Ang III, induces equivalent anti-fibrotic effects to Compound 21 but broader anti-fibrotic effects than pirfenidone in mice with bleomycin-induced pulmonary fibrosis.

新型 AT2 受体配体 β-Pro7 Ang III 在博来霉素诱导的小鼠肺纤维化模型中,其抗纤维化作用与化合物 21 相当,但比吡非尼酮的作用范围更广

Royce Simon G, Erdem Cem, Mao WeiYi, Wang Yan, Del Borgo Mark P, Widdop Robert E, Samuel Chrishan S

The renoprotective efficacy and safety of genetically-engineered human bone marrow-derived mesenchymal stromal cells expressing anti-fibrotic cargo

表达抗纤维化物质的基因工程人类骨髓间充质基质细胞的肾脏保护功效和安全性

Yifang Li, Alex Hunter, Miqdad M Wakeel, Guizhi Sun, Ricky W K Lau, Brad R S Broughton, Ivan E Oyarce Pino, Zihao Deng, Tingfang Zhang, Padma Murthi, Mark P Del Borgo, Robert E Widdop, Jose M Polo, Sharon D Ricardo, Chrishan S Samuel3

Sex- and time-dependent role of insulin regulated aminopeptidase in lipopolysaccharide-induced inflammation

胰岛素调节氨基肽酶在脂多糖诱导的炎症中性别和时间依赖性的作用

Anika Vear, Amlan Chakraborty, Farnaz Fahimi, Dorota Ferens, Robert Widdop, Chrishan S Samuel, Tracey Gaspari, Peter M van Endert, Siew Yeen Chai

Anti-inflammatory and anti-fibrotic effects of berberine-loaded liquid crystalline nanoparticles

载有小檗碱的液晶纳米粒子的抗炎和抗纤维化作用

Amlan Chakraborty ,Keshav Raj Paudel ,Chao Wang ,Gabriele De Rubis ,Dinesh Kumar Chellappan ,Philip Michael Hansbro ,Chrishan S Samuel ,Kamal Dua

IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages

IL-4 和 IL-13 诱导人类巨噬细胞中传统 M2 标志物的等效表达和活性氧的调节

Tara E Scott #, Caitlin V Lewis #, Mingyu Zhu, Chao Wang, Chrishan S Samuel, Grant R Drummond, Barbara K Kemp-Harper

Comparative Study of Ectopic Lymphoid Aggregates in Sheep and Murine Models of Bleomycin-Induced Pulmonary Fibrosis

绵羊和小鼠博来霉素诱发肺纤维化模型中异位淋巴细胞聚集体的比较研究

Udari Eshani Perera, Louise Organ, Simon G Royce, Chrishan S Samuel, Habtamu B Derseh, Sasika N V Dewage, Emmanuel Koumoundouros, Andrew Stent, Kenneth J Snibson

A Lipidated Single-B-Chain Derivative of Relaxin Exhibits Improved In Vitro Serum Stability without Altering Activity

松弛素的脂化单 B 链衍生物表现出改善的体外血清稳定性而不改变活性

Praveen Praveen, Chao Wang, Thomas N G Handley, Hongkang Wu, Chrishan S Samuel, Ross A D Bathgate, Mohammed Akhter Hossain

Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms

萝卜硫素通过抗炎、抗氧化和表观遗传机制预防和逆转小鼠过敏性气道疾病。

Royce, Simon G; Licciardi, Paul V; Beh, Raymond C; Bourke, Jane E; Donovan, Chantal; Hung, Andrew; Khurana, Ishant; Liang, Julia J; Maxwell, Scott; Mazarakis, Nadia; Pitsillou, Eleni; Siow, Ya Yun; Snibson, Kenneth J; Tobin, Mark J; Ververis, Katherine; Vongsvivut, Jitraporn; Ziemann, Mark; Samuel, Chrishan S; Tang, Mimi L K; El-Osta, Assam; Karagiannis, Tom C

The Placental NLRP3 Inflammasome and Its Downstream Targets, Caspase-1 and Interleukin-6, Are Increased in Human Fetal Growth Restriction: Implications for Aberrant Inflammation-Induced Trophoblast Dysfunction

胎盘 NLRP3 炎症小体及其下游靶点 Caspase-1 和白细胞介素-6 在人类胎儿生长受限中增加:对异常炎症诱发的滋养细胞功能障碍的影响

Irvan Alfian, Amlan Chakraborty, Hannah E J Yong, Sheetal Saini, Ricky W K Lau, Bill Kalionis, Evdokia Dimitriadis, Nadia Alfaidy, Sharon D Ricardo, Chrishan S Samuel, Padma Murthi