日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Iron-associated lipid peroxidation in Alzheimer's disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice

在阿尔茨海默病中,铁相关的脂质过氧化作用在脂筏中增强,而铁死亡抑制因子减少,这一现象已通过小鼠螯合实验得到证实。

Thorwald, Max A; Godoy-Lugo, Jose A; Garcia, Gilberto; Silva, Justine; Kim, Minhoo; Christensen, Amy; Mack, Wendy J; Head, Elizabeth; O'Day, Peggy A; Benayoun, Bérénice A; Morgan, Todd E; Pike, Christian J; Higuchi-Sanabria, Ryo; Forman, Henry Jay; Finch, Caleb E

Aging murine peritoneal macrophages undergo female-specific remodeling driven by hormone-dependent and independent mechanisms.

衰老的小鼠腹膜巨噬细胞会经历由激素依赖性和非依赖性机制驱动的雌性特异性重塑

Lu Ryan J, Chen Shiqi, Kim Minhoo, Sampathkumar Nirmal K, Lee Evelyn H, Christensen Amy, Wang Eric E, Lau Isabella Y, Parihar Shivay, Ravikumar Charan K, Jung Jane, Brown Shelby, Xu Alan, Alvarenga Julio L, Mehalko Kristen, Lee Changhan D, Goodridge Helen S, Benayoun Bérénice A

Protection against APOE4-associated phenotypes with the longevity-promoting intervention 17α-estradiol in middle-aged male mice.

在中年雄性小鼠中,通过促进寿命的干预措施 17α-雌二醇来预防 APOE4 相关表型

McGill Cassandra J, Christensen Amy, Qian Wenjie, Thorwald Max A, Lugo Jose Godoy, Namvari Sara, White Olivia S, Finch Caleb E, Benayoun Bérénice A, Pike Christian J

Effects of obesogenic diet and 17β-estradiol in female mice with APOE 3/3, 3/4, and 4/4 genotypes

肥胖饮食和17β-雌二醇对APOE 3/3、3/4和4/4基因型雌性小鼠的影响

Christensen, Amy; McGill, Cassandra J; Qian, Wenjie; Pike, Christian J

Apolipoprotein E polymorphisms and female fertility in a transgenic mouse model of Alzheimer's disease

载脂蛋白E多态性与阿尔茨海默病转基因小鼠模型雌性生育力的关系

Medegan Fagla, Bani; York, Jason; Christensen, Amy; Dela Rosa, Cielo; Balu, Deebika; Pike, Christian J; Tai, Leon M; Buhimschi, Irina A

Role of estrogen in women's Alzheimer's disease risk as modified by APOE

雌激素在女性阿尔茨海默病风险中的作用及其受APOE基因的影响

Valencia-Olvera, Ana C; Maldonado Weng, Juan; Christensen, Amy; LaDu, Mary Jo; Pike, Christian J

Aging Reduces Estradiol Protection Against Neural but Not Metabolic Effects of Obesity in Female 3xTg-AD Mice

衰老会降低雌二醇对肥胖引起的神经系统影响的保护作用,但不会降低其对代谢的影响(在雌性 3xTg-AD 小鼠中)。

Christensen, Amy; Liu, Jiahui; Pike, Christian J

Isotopic Fractionation of Potassium by Diffusion in Methanol

甲醇中钾同位素扩散分馏

John N Christensen, Amy E Hofmann, Donald J DePaolo

Effects of aging, high-fat diet, and testosterone treatment on neural and metabolic outcomes in male brown Norway rats

衰老、高脂饮食和睾酮治疗对雄性褐挪威大鼠神经和代谢结果的影响

Moser, V Alexandra; Christensen, Amy; Liu, Jiahui; Zhou, Amanda; Yagi, Shunya; Beam, Christopher R; Galea, Liisa; Pike, Christian J

The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice

APOE4等位基因在人类和小鼠的微出血和阿尔茨海默病中表现出相反的性别偏向性。

Cacciottolo, Mafalda; Christensen, Amy; Moser, Alexandra; Liu, Jiahui; Pike, Christian J; Smith, Conor; LaDu, Mary Jo; Sullivan, Patrick M; Morgan, Todd E; Dolzhenko, Egor; Charidimou, Andreas; Wahlund, Lars-Olof; Wiberg, Maria Kristofferson; Shams, Sara; Chiang, Gloria Chia-Yi; Finch, Caleb E