日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice.

阻止 BMP4 前结构域磷酸化的突变会损害同源二聚体的蛋白水解成熟,从而导致小鼠死亡

Kim Hyung-Seok, Sanchez Mary L, Silva Joshua, Schubert Heidi L, Dennis Rebecca, Hill Christopher P, Christian Jan L

MuSK Regulates Neuromuscular Junction Nav1.4 Localization and Excitability

MuSK调节神经肌肉接头Nav1.4的定位和兴奋性

Fish, Lauren A; Ewing, Madison D; Rich, Kelly A; Xi, Chengjie; Chen, Isabella; Jaime, Diego; Madigan, Laura A; Wang, Xueyong; Shahtout, Justin L; Feder, Rita E; Funai, Katsuhiko; Christian, Jan L; Wharton, Kristi A; Rich, Mark M; Arnold, William D; Fallon, Justin R

In vivo variability of MRI radiomics features in prostate lesions assessed by a test-retest study with repositioning

通过重新定位的测试-再测试研究评估前列腺病变中MRI放射组学特征的体内变异性

Zhang, Kevin Sun; Neelsen, Christian Jan Oliver; Wennmann, Markus; Hielscher, Thomas; Kovacs, Balint; Glemser, Philip Alexander; Görtz, Magdalena; Stenzinger, Albrecht; Maier-Hein, Klaus H; Huber, Johannes; Schlemmer, Heinz-Peter; Bonekamp, David

Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice

阻止BMP4前结构域磷酸化的突变会损害同源二聚体的蛋白水解成熟,从而导致小鼠死亡。

Kim, Hyung-Seok; Sanchez, Mary L; Silva, Joshua; Schubert, Heidi L; Dennis, Rebecca; Hill, Christopher P; Christian, Jan L

The prodomain of bone morphogenetic protein 2 promotes dimerization and cleavage of BMP6 homodimers and BMP2/6 heterodimers

骨形态发生蛋白2的前结构域促进BMP6同源二聚体和BMP2/6异源二聚体的二聚化和裂解。

Chauhan, Pooja; Xue, Yongqiang; Kim, Hyung-Seok; Fisher, Allison L; Babitt, Jodie L; Christian, Jan L

Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l.

Tril 通过 Pellino2 和 Traf6 介导的 Nedd4l 激活来抑制 Nodal 信号传导。

Kim Hyung-Seok, Green Yangsook Song, Xie Yuanyuan, Christian Jan L

Analysis of Transforming Growth Factor ß Family Cleavage Products Secreted Into the Blastocoele of Xenopus laevis Embryos.

对非洲爪蟾胚胎囊胚腔中分泌的转化生长因子家族裂解产物的分析

Kim Hyung-Seok, Christian Jan L

Tril targets Smad7 for degradation to allow hematopoietic specification in Xenopus embryos.

Tril 靶向 Smad7 使其降解,从而实现非洲爪蟾胚胎的造血分化

Green Yangsook Song, Kwon Sunjong, Mimoto Mizuho S, Xie Yuanyuan, Christian Jan L

PKC/ROS-Mediated NLRP3 Inflammasome Activation Is Attenuated by Leishmania Zinc-Metalloprotease during Infection

在感染过程中,利什曼原虫锌金属蛋白酶可减弱 PKC/ROS 介导的 NLRP3 炎症小体激活。

Shio, Marina Tiemi; Christian, Jan Gregor; Jung, Jee Yong; Chang, Kwang-Poo; Olivier, Martin

MYC and EGR1 synergize to trigger tumor cell death by controlling NOXA and BIM transcription upon treatment with the proteasome inhibitor bortezomib.

MYC 和 EGR1 协同作用,通过控制 NOXA 和 BIM 转录,在用蛋白酶体抑制剂硼替佐米治疗时触发肿瘤细胞死亡

Wirth Matthias, Stojanovic Natasa, Christian Jan, Paul Mariel C, Stauber Roland H, Schmid Roland M, Häcker Georg, Krämer Oliver H, Saur Dieter, Schneider Günter