日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integrins Increase Sarcoplasmic Reticulum Activity for Excitation-Contraction Coupling in Human Stem Cell-Derived Cardiomyocytes

整合素增加人类干细胞衍生的心肌细胞中兴奋-收缩偶联的肌浆网活性

Brian X Wang, Christopher Kane, Laura Nicastro, Oisín King, Worrapong Kit-Anan, Barrett Downing, Graziano Deidda, Liam S Couch, Christian Pinali, Anna Mitraki, Kenneth T MacLeod, Cesare M Terracciano

Cardiac mitochondrial function depends on BUD23 mediated ribosome programming

心脏线粒体功能依赖于BUD23介导的核糖体编程。

Matthew Baxter ,Maria Voronkov ,Toryn Poolman ,Gina Galli ,Christian Pinali ,Laurence Goosey ,Abigail Knight ,Karolina Krakowiak ,Robert Maidstone ,Mudassar Iqbal ,Min Zi ,Sukhpal Prehar ,Elizabeth J Cartwright ,Julie Gibbs ,Laura C Matthews ,Antony D Adamson ,Neil E Humphreys ,Pedro Rebelo-Guiomar ,Michal Minczuk ,David A Bechtold ,Andrew Loudon ,David Ray

Human junctophilin-2 undergoes a structural rearrangement upon binding PtdIns(3,4,5)P3 and the S101R mutation identified in hypertrophic cardiomyopathy obviates this response

人类 junctophilin-2 在与 PtdIns(3,4,5)P3 结合后会发生结构重排,而肥厚性心肌病中发现的 S101R 突变可消除这种反应

Hayley J Bennett, John Bernard Davenport, Richard F Collins, Andrew W Trafford, Christian Pinali, Ashraf Kitmitto