日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phenotypic and functional characteristics of monocyte subsets in the blood and bone marrow of Indian subjects with Visceral Leishmaniasis

印度内脏利什曼病患者血液和骨髓中单核细胞亚群的表型和功能特征

Gulafsha Kausar, Shashi Bhushan Chauhan, Ritirupa Roy, Vimal Verma, Sundaram Pandey, Aziza Niyaz, Jaya Chakravarty, Christian R Engwerda, Susanne Nylen, Rajiv Kumar, Mary E Wilson, Shyam Sundar

Single cell transcriptomics shows that malaria promotes unique regulatory responses across multiple immune cell subsets

单细胞转录组学表明疟疾促进多个免疫细胞亚群的独特调节反应

Nicholas L Dooley #, Tinashe G Chabikwa #, Zuleima Pava, Jessica R Loughland, Julianne Hamelink, Kiana Berry, Dean Andrew, Megan S F Soon, Arya SheelaNair, Kim A Piera, Timothy William, Bridget E Barber, Matthew J Grigg, Christian R Engwerda, J Alejandro Lopez, Nicholas M Anstey, Michelle J Boyle2

Increased amphiregulin expression by CD4+ T cells from individuals with asymptomatic Leishmania donovani infection

无症状利什曼原虫感染者CD4+ T细胞中双调蛋白表达增加

Siddharth Sankar Singh ,Shashi Bhushan Chauhan ,Susanna Ss Ng ,Dillon Corvino ,Fabian de Labastida Rivera ,Jessica A Engel ,Nic Waddell ,Pamela Mukhopadhay ,Rebecca L Johnston ,Lambros T Koufariotis ,Susanne Nylen ,Om Prakash Singh ,Christian R Engwerda ,Rajiv Kumar ,Shyam Sundar

Novel antiinflammatory biologics shaped by parasite-host coevolution

由寄生虫-宿主共同进化形成的新型抗炎生物制剂

Stephanie M Ryan, Roland Ruscher, Wayne A Johnston, Darren A Pickering, Malcolm W Kennedy, Brian O Smith, Linda Jones, Geraldine Buitrago, Matt A Field, Adrian J Esterman, Connor P McHugh, Daniel J Browne, Martha M Cooper, Rachael Y M Ryan, Denise L Doolan, Christian R Engwerda, Kim Miles, Makedonka

Reduced circulating dendritic cells in acute Plasmodium knowlesi and Plasmodium falciparum malaria despite elevated plasma Flt3 ligand levels

尽管血浆 Flt3 配体水平升高,急性诺氏疟原虫和恶性疟原虫疟疾中的循环树突状细胞减少

Jessica R Loughland, Tonia Woodberry, Damian Oyong, Kim A Piera, Fiona H Amante, Bridget E Barber, Matthew J Grigg, Timothy William, Christian R Engwerda, Nicholas M Anstey, James S McCarthy, Michelle J Boyle, Gabriela Minigo

Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria

感染诱导的浆母细胞是一种营养库,会削弱对疟疾的体液免疫

Rahul Vijay #, Jenna J Guthmiller #, Alexandria J Sturtz, Fionna A Surette, Kai J Rogers, Ramakrishna R Sompallae, Fengyin Li, Rosemary L Pope, Jo-Anne Chan, Fabian de Labastida Rivera, Dean Andrew, Lachlan Webb, Wendy J Maury, Hai-Hui Xue, Christian R Engwerda, James S McCarthy, Michelle J Boyle, N

Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis

Bach2通过减弱TCR诱导的转录来调控调节性T细胞的分化和稳态。

Tom Sidwell ,Yang Liao ,Alexandra L Garnham ,Ajithkumar Vasanthakumar ,Renee Gloury ,Jonas Blume ,Peggy P Teh ,David Chisanga ,Christoph Thelemann ,Fabian de Labastida Rivera ,Christian R Engwerda ,Lynn Corcoran ,Kohei Kometani ,Tomohiro Kurosaki ,Gordon K Smyth ,Wei Shi ,Axel Kallies

Th2-like T Follicular Helper Cells Promote Functional Antibody Production during Plasmodium falciparum Infection

Th2样滤泡辅助性T细胞在恶性疟原虫感染期间促进功能性抗体的产生

Jo-Anne Chan ,Jessica R Loughland ,Fabian de Labastida Rivera ,Arya SheelaNair ,Dean W Andrew ,Nicholas L Dooley ,Bruce D Wines ,Fiona H Amante ,Lachlan Webb ,P Mark Hogarth ,James S McCarthy ,James G Beeson ,Christian R Engwerda ,Michelle J Boyle

Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

I型干扰素抑制抗寄生虫免疫,可作为改善内脏利什曼病治疗的靶点。

Rajiv Kumar ,Patrick T Bunn ,Siddharth Sankar Singh ,Susanna S Ng ,Marcela Montes de Oca ,Fabian De Labastida Rivera ,Shashi Bhushan Chauhan ,Neetu Singh ,Rebecca J Faleiro ,Chelsea L Edwards ,Teija C M Frame ,Meru Sheel ,Rebecca J Austin ,Steven W Lane ,Tobias Bald ,Mark J Smyth ,Geoffrey R Hill ,Shannon E Best ,Ashraful Haque ,Dillon Corvino ,Nic Waddell ,Lambross Koufariotis ,Pamela Mukhopadhay ,Madhukar Rai ,Jaya Chakravarty ,Om Prakash Singh ,David Sacks ,Susanne Nylen ,Jude Uzonna ,Shyam Sundar ,Christian R Engwerda

IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection

IL-27信号通路调节Th1细胞的糖酵解,从而限制感染期间的免疫病理反应。

Marcela Montes de Oca ,Fabian de Labastida Rivera ,Clay Winterford ,Teija C M Frame ,Susanna S Ng ,Fiona H Amante ,Chelsea L Edwards ,Luzia Bukali ,Yulin Wang ,Jude E Uzonna ,Rachel D Kuns ,Ping Zhang ,Agnieszka Kabat ,Ramon I Klein Geltink ,Edward J Pearce ,Geoffrey R Hill ,Christian R Engwerda