日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Directing the migration of serum-free, ex vivo-expanded Vγ9Vδ2 T cells

引导无血清、体外扩增的Vγ9Vδ2 T细胞的迁移

Kiran K Parwani ,Gianna M Branella ,Rebecca E Burnham ,Andre J Burnham ,Austre Y Schiaffino Bustamante ,Elisabetta Manuela Foppiani ,Kristopher A Knight ,Brian G Petrich ,Edwin M Horwitz ,Christopher B Doering ,H Trent Spencer

Transplanting FVIII/ET3-secreting cells in fetal sheep increases FVIII levels long-term without inducing immunity or toxicity

将分泌FVIII/ET3的细胞移植到胎羊体内,可长期提高FVIII水平,且不诱发免疫反应或毒性。

Martin Rodriguez,Brady Trevisan,Ritu M Ramamurthy,Sunil K George,Jonathan Diaz,Jordan Alexander,Diane Meares,Denise J Schwahn,David R Quilici,Jorge Figueroa,Michael Gautreaux,Andrew Farland,Anthony Atala,Christopher B Doering,H Trent Spencer,Christopher D Porada #,Graça Almeida-Porada #

Identification and targeting of protein tyrosine kinase 7 (PTK7) as an immunotherapy candidate for neuroblastoma

鉴定并靶向蛋白酪氨酸激酶7 (PTK7) 作为神经母细胞瘤的免疫治疗候选靶点

Jasmine Y Lee ,Hunter C Jonus ,Arhanti Sadanand ,Gianna M Branella ,Victor Maximov ,Suttipong Suttapitugsakul ,Matthew J Schniederjan ,Jenny Shim ,Andrew Ho ,Kiran K Parwani ,Andrew Fedanov ,Adeiye A Pilgrim ,Jordan A Silva ,Robert W Schnepp ,Christopher B Doering ,Ronghu Wu ,H Trent Spencer ,Kelly C Goldsmith

Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia

使用工程化的 γδ T 细胞以配体为基础靶向 c-kit 作为治疗急性髓系白血病的策略

Gianna M Branella, Jasmine Y Lee, Jennifer Okalova, Kiran K Parwani, Jordan S Alexander, Raquel F Arthuzo, Andrew Fedanov, Bing Yu, David McCarty, Harrison C Brown, Shanmuganathan Chandrakasan, Brian G Petrich, Christopher B Doering, H Trent Spencer

SAXS analysis of the intrinsic tenase complex bound to a lipid nanodisc highlights intermolecular contacts between factors VIIIa/IXa

与脂质纳米盘结合的内在 Tenase 复合物的 SAXS 分析突出了因子 VIIIa/IXa 之间的分子间接触

Kenneth C Childers, Shaun C Peters, Pete Lollar, Harold Trent Spencer, Christopher B Doering, Paul C Spiegel

Comparison of different gene addition strategies to modify placental derived-mesenchymal stromal cells to produce FVIII

比较不同的基因添加策略来修饰胎盘来源的间充质基质细胞以产生 FVIII

Ritu M Ramamurthy, Martin Rodriguez, Hannah C Ainsworth, Jordan Shields, Diane Meares, Colin Bishop, Andrew Farland, Carl D Langefeld, Anthony Atala, Christopher B Doering, H Trent Spencer, Christopher D Porada, Graça Almeida-Porada

Identification of coagulation factor IX variants with enhanced activity through ancestral sequence reconstruction

通过祖先序列重建鉴定活性增强的凝血因子 IX 变体

Kristopher A Knight, Christopher W Coyle, Caelan E Radford, Ernest T Parker, Andrew Fedanov, Jordan M Shields, Fania Szlam, Anatolii Purchel, Michelle Chen, Gabriela Denning, Roman M Sniecinski, Pete Lollar, H Trent Spencer, Eric A Gaucher, Christopher B Doering

Molecular coevolution of coagulation factor VIII and von Willebrand factor

凝血因子 VIII 和血管性血友病因子的分子协同进化

Philip M Zakas, Christopher W Coyle, Anja Brehm, Marion Bayer, Barbara Solecka-Witulska, Caelan E Radford, Christine Brown, Kate Nesbitt, Courtney Dwyer, Christoph Kannicht, H Trent Spencer, Eric A Gaucher, Christopher B Doering, David Lillicrap

Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A

研究用于产前或围产期输送VIII因子治疗A型血友病的最佳自体细胞平台

Christopher Stem,Christopher Rodman,Ritu M Ramamurthy,Sunil George,Diane Meares,Andrew Farland,Anthony Atala,Christopher B Doering,H Trent Spencer,Christopher D Porada,Graça Almeida-Porada

Bortezomib enhances cytotoxicity of ex vivo-expanded gamma delta T cells against acute myeloid leukemia and T-cell acute lymphoblastic leukemia

硼替佐米可增强体外扩增的γδT细胞对急性髓系白血病和T细胞急性淋巴细胞白血病的细胞毒性

Jamie Y Story, Jaquelyn T Zoine, Rebecca E Burnham, Jamie A G Hamilton, H Trent Spencer, Christopher B Doering, Sunil S Raikar