日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural insights into WRN helicase reveal conformational states and opportunities for MSI-H cancer drug discovery

对WRN解旋酶的结构解析揭示了其构象状态,并为MSI-H癌症药物研发提供了契机。

Fletcher, Catherine T; Mornement, Abigail A; Barrett, Charlotte; Canning, Peter; Rucktooa, Prakash; Huber, Sophie; Cooper, Christopher D O; Scully, Conor C G; Doré, Andrew S; Rohle, Daniel; Smith, Geoffrey M T; Skerratt, Sarah E; Kennedy, Amanda J

Borrelia BBJ25 is a plasmid-encoded Omp85-family protein associated with a potential export system

伯氏疏螺旋体BBJ25是一种质粒编码的Omp85家族蛋白,与潜在的输出系统相关。

Nixon, Abigail; Soliman, Evelina; Bryk, Jaroslaw; Carr, Martin; Cooper, Christopher D O; Bingham, Richard J

Escherichia coli DNA repair helicase Lhr is also a uracil-DNA glycosylase

大肠杆菌DNA修复解旋酶Lhr也是一种尿嘧啶-DNA糖苷酶

Buckley, Ryan J; Lou-Hing, Anna; Hanson, Karl M; Ahmed, Nadia R; Cooper, Christopher D O; Bolt, Edward L

Crystal structure and molecular dynamics of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability

人类 POLDIP2 的晶体结构和分子动力学研究:一种在代谢和基因组稳定性中发挥重要作用的多功能衔接蛋白

Kulik, Anastasija A; Maruszczak, Klaudia K; Thomas, Dana C; Nabi-Aldridge, Naomi L A; Carr, Martin; Bingham, Richard J; Cooper, Christopher D O

A new chapter for a better Bioscience Reports

生物科学报告的新篇章

Cooper, Christopher D O; Han, Weiping

The HelQ human DNA repair helicase utilizes a PWI-like domain for DNA loading through interaction with RPA, triggering DNA unwinding by the HelQ helicase core

HelQ 人类 DNA 修复解旋酶利用 PWI 样结构域与 RPA 相互作用加载 DNA,从而触发 HelQ 解旋酶核心解开 DNA。

Jenkins, Tabitha; Northall, Sarah J; Ptchelkine, Denis; Lever, Rebecca; Cubbon, Andrew; Betts, Hannah; Taresco, Vincenzo; Cooper, Christopher D O; McHugh, Peter J; Soultanas, Panos; Bolt, Edward L

Mechanistic insights into Lhr helicase function in DNA repair

对Lhr解旋酶在DNA修复中功能的机制性见解

Buckley, Ryan J; Kramm, Kevin; Cooper, Christopher D O; Grohmann, Dina; Bolt, Edward L

MicroRNA Quantitation During Dendritic Cell Endocytosis Using Imaging Flow Cytometry: Key Factors and Requirements

使用成像流式细胞术对树突状细胞内吞过程中的 microRNA 进行定量分析:关键因素和要求

Qiang Tong, Ying Zhu, Dandan Zhang, Qing Cai, Wenchun Qu, Christopher D O Cooper, Jiaqi Wang, Patrick C McHugh

Structural insights into the function of ZRANB3 in replication stress response

ZRANB3 在复制应激反应中功能的结构洞察

Marek Sebesta, Christopher D O Cooper, Antonio Ariza, Christopher J Carnie, Dragana Ahel

Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding

两种黑色素瘤相关抗原的结构表明效应子结合的变构调节

Joseph A Newman, Christopher D O Cooper, Anette K Roos, Hazel Aitkenhead, Udo C T Oppermann, Hearn J Cho, Roman Osman, Opher Gileadi