日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A cGAS-dependent response links DNA damage and senescence in alveolar epithelial cells: a potential drug target in IPF

cGAS 依赖性反应将肺泡上皮细胞中的 DNA 损伤与衰老联系起来:特发性肺纤维化 (IPF) 的潜在药物靶点

Michael Schuliga, Amama Kanwal, Jane Read, Kaj E C Blokland, Janette K Burgess, Cecilia M Prêle, Steven E Mutsaers, Christopher Grainge, Claire Thomson, Allen James, Nathan W Bartlett, Darryl A Knight

Self DNA perpetuates IPF lung fibroblast senescence in a cGAS-dependent manner

自身 DNA 以 cGAS 依赖的方式延续 IPF 肺成纤维细胞衰老

Michael Schuliga, Jane Read, Kaj E C Blokland, David W Waters, Janette Burgess, Cecilia Prêle, Steven E Mutsaers, Jade Jaffar, Glen Westall, Andrew Reid, Allen James, Christopher Grainge, Darryl A Knight

Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts

线粒体功能障碍导致 IPF 肺成纤维细胞衰老表型

Michael Schuliga, Dmitri V Pechkovsky, Jane Read, David W Waters, Kaj E C Blokland, Andrew T Reid, Cory M Hogaboam, Nasreen Khalil, Janette K Burgess, Cecilia M Prêle, Steven E Mutsaers, Jade Jaffar, Glen Westall, Christopher Grainge, Darryl A Knight

Disease progression in idiopathic pulmonary fibrosis with mild physiological impairment: analysis from the Australian IPF registry

轻度生理功能障碍的特发性肺纤维化疾病进展:来自澳大利亚特发性肺纤维化登记处的分析

Jo, Helen E; Glaspole, Ian; Moodley, Yuben; Chapman, Sally; Ellis, Samantha; Goh, Nicole; Hopkins, Peter; Keir, Greg; Mahar, Annabelle; Cooper, Wendy; Reynolds, Paul; Haydn Walters, E; Zappala, Christopher; Grainge, Christopher; Allan, Heather; Macansh, Sacha; Corte, Tamera J

Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity

膜联蛋白 A2 通过增强 Xa 因子纤维化活性导致肺损伤和纤维化

Michael Schuliga, Jade Jaffar, Asres Berhan, Shenna Langenbach, Trudi Harris, David Waters, Peter V S Lee, Christopher Grainge, Glen Westall, Darryl Knight, Alastair G Stewart

Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma

难治性重度哮喘中潜在致病性气道细菌和中性粒细胞炎症

Benjamin J Green, Surasa Wiriyachaiporn, Christopher Grainge, Geraint B Rogers, Valia Kehagia, Laurie Lau, Mary P Carroll, Kenneth D Bruce, Peter H Howarth