日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cross-tissue comparison of telomere length and quality metrics of DNA among individuals aged 8 to 70 years

8至70岁个体间端粒长度和DNA质量指标的跨组织比较

Wolf, Sarah E; Hastings, Waylon J; Ye, Qiaofeng; Etzel, Laura; Apsley, Abner T; Chiaro, Christopher; Heim, Christine C; Heller, Thomas; Noll, Jennie G; Schreier, Hannah M C; Shenk, Chad E; Shalev, Idan

Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

利用配体的亲和力和特性:发现用于 PROTAC 设计的新型苯甲酰胺型 Cereblon 结合剂

Christian Steinebach, Aleša Bricelj, Arunima Murgai, Izidor Sosič, Luca Bischof, Yuen Lam Dora Ng, Christopher Heim, Samuel Maiwald, Matic Proj, Rabea Voget, Felix Feller, Janez Košmrlj, Valeriia Sapozhnikova, Annika Schmidt, Maximilian Rudolf Zuleeg, Patricia Lemnitzer, Philipp Mertins, Finn K Hans

De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives

以沙利度胺衍生物的天然水解产物为指导的 Cereblon (CRBN) 效应物的从头设计

Christopher Heim, Dimanthi Pliatsika, Farnoush Mousavizadeh, Kerstin Bär, Birte Hernandez Alvarez, Athanassios Giannis, Marcus D Hartmann

Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G

乳铁蛋白是组织蛋白酶 G 蛋白水解活性的变构增强剂

Steffen Eipper, Robin Steiner, Adam Lesner, Marcin Sienczyk, David Palesch, Marc-Eric Halatsch, Ewa Zaczynska, Christopher Heim, Marcus D Hartmann, Michal Zimecki, Christian Rainer Wirtz, Timo Burster