日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing

针对 Tau Pre-mRNA 并影响剪接的小分子的设计、优化和研究

Jonathan L Chen, Peiyuan Zhang, Masahito Abe, Haruo Aikawa, Liying Zhang, Alexander J Frank, Timothy Zembryski, Christopher Hubbs, HaJeung Park, Jane Withka, Claire Steppan, Lucy Rogers, Shawn Cabral, Martin Pettersson, Travis T Wager, Matthew A Fountain, Gavin Rumbaugh, Jessica L Childs-Disney, Mat

A Simple Procedure for Creating Scalable Phenotypic Screening Assays in Human Neurons

在人类神经元中创建可扩展表型筛选检测的简单程序

BanuPriya Sridharan, Christopher Hubbs, Nerea Llamosas, Murat Kilinc, Fakhar U Singhera, Erik Willems, David R Piper, Louis Scampavia, Gavin Rumbaugh, Timothy P Spicer

Neuronal death induced by misfolded prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment

错误折叠的朊病毒蛋白引起的神经元死亡是由于 NAD+ 耗竭造成的,可以通过体外和体内 NAD+ 补充来缓解

Minghai Zhou, Gregory Ottenberg, Gian Franco Sferrazza, Christopher Hubbs, Mohammad Fallahi, Gavin Rumbaugh, Alicia F Brantley, Corinne I Lasmézas